Axons are generally considered as reliable transmission cables in which stable propagation
occurs once an action potential is generated. Axon dysfunction occupies a central position in …

Stroke is the leading cause of adult disability. Yet there is a limited degree of recovery in this
disease. One of the mechanisms of recovery is the formation of new connections in the brain …

Norepinephrine (NE) is synthesized in the locus coeruleus and widely projected throughout
the brain and spinal cord. It regulates various actions and consciousness linked to a variety …

The origin and mechanisms of human interictal epileptic discharges remain unclear. Here,
we describe a spontaneous, rhythmic activity initiated in the subiculum of slices from patients …

An account of the neurobiology of motor recovery in the arm and hand after stroke by two
experts in the field. Stroke is a leading cause of disability in adults and recovery is often …

We investigated the influence of synaptically released glutamate on postsynaptic structure
by comparing the effects of deafferentation, receptor antagonists and blockers of glutamate …

Epilepsies are a diverse collection of brain disorders that affect 1–2% of the population.
Current therapies are unsatisfactory as they provide only symptomatic relief, are effective in …

The most common type of epilepsy in adults is temporal lobe epilepsy. After epileptogenic
injuries, dentate granule cell axons (mossy fibers) sprout and form new synaptic …

Traumatic brain injury (TBI) and status epilepticus (SE) have both been linked to
development of human epilepsy. Although distinct etiologies, current research has …

▪ Abstract The precise regulation of neural excitability is essential for proper nerve cell,
neural circuit, and nervous system function. During postembryonic development and …