Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Millions of experimental animals are widely used in the assessment of toxicological or
biological effects of manufactured nanomaterials in medical technology. However, the …

For the past decades, heart diseases remain the leading cause of death worldwide. In the
adult mammalian heart, damaged cardiomyocytes will be replaced by non-contractile fibrotic …

Cellular models have created opportunities to explore the characteristics of human diseases
through well-established protocols, while avoiding the ethical restrictions associated with …

Cardiovascular diseases represent a major socio-economic burden. In recent years,
considerable effort has been invested in optimizing cell delivery strategies to advance cell …

Cardiac patches are biomaterials that can be used for transplantation and repair of
damaged myocardium by combining seed cells with the ability to form cardiomyocytes and …

Cardiovascular diseases (CVDs) are globally known to be important causes of mortality and
disabilities. Common treatment strategies for CVDs, such as pharmacological therapeutics …

Cardiovascular diseases (CVDs) have been the leading cause of death worldwide during
the past several decades. Cell loss is the main problem that results in cardiac dysfunction …

Ischemic heart disease (IHD) is defined as a syndrome of ischemic cardiomyopathy.
Myogenesis and angiogenesis in the ischemic myocardium are important for cardiomyocyte …

Chronic disease can cause tissue and organ damage constituting the largest obstacle to
therapy which, in turn, reduces patients' quality-adjusted life-year. Degenerative diseases …