Extensive research has been conducted on the isolation and study of bioactive compounds
derived from marine sources. Several natural products have demonstrated potential as …

A short and flexible construction of novel dihydrosphingosine-type analogues has been
accomplished. The pivotal step of this approach was a cascade [3, 3]-sigmatropic …

All four stereoisomers of sphinganine can be synthesized by a multicomponent aziridination
of an aldehyde, an amine and an α-diazo carbonyl compound mediated by a BOROX …

Two approaches to a small library of cytotoxic dihydrosphingosine analogues are
described.[3, 3]-Sigmatropic rearrangements along with an OCM reaction were used as the …

A straightforward synthetic pathway allowing the access to anti or syn 2-amino-1, 3-diol
scaffolds is presented. The strategy relies on a diastereoselective organocatalyzed …

This review highlights the proline-catalyzed asymmetric α-hydroxylation of aldehydes
derived from amino acids. This reaction provides a robust method for introducing a hydroxyl …

Enantioselective syntheses of (R)‐antofine and (R)‐cryptopleurine starting from a 3‐
phenanthrenylpropanal derivative are reported. Asymmetric α‐amination of this aldehyde is …

Tato práce popisuje přípravu jednotlivých diastereoizomerů vybraných 2-aminoalkan-3-olů,
neboli 1-deoxysfingosinových bází, v racemické formě. Syntéza těchto sloučenin je …

A short asymmetric synthesis of sphinganine [(2 S, 3R)-2-aminooctadecane-1, 3-diol] and its
C (2)-epimer is reported. The synthesis of sphinganine employs diastereoselective …

A convenient and efficient method for the synthesis of (–)-bestatin, epibestatin, phebestin,
and (3S, 4R)-4-amino-3-hydroxy-5-phenylpentanoic acid is reported. The key step is a …