Photodynamic therapy in oral cancer: A review of clinical studies

SA Mosaddad, RA Namanloo, SS Aghili, P Maskani… - Medical Oncology, 2023 - Springer
A significant mortality rate is associated with oral cancer, particularly in cases of late-stage
diagnosis. Since the last decades, oral cancer survival rates have only gradually improved …

New photosensitizers for photodynamic therapy

H Abrahamse, MR Hamblin - Biochemical Journal, 2016 - portlandpress.com
Photodynamic therapy (PDT) was discovered more than 100 years ago, and has since
become a well-studied therapy for cancer and various non-malignant diseases including …

The great escape: how cationic polyplexes overcome the endosomal barrier

T Bus, A Traeger, US Schubert - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
The targeted and efficiency-oriented delivery of (therapeutic) nucleic acids raises hope for
successful gene therapy, ie, for the local and individual treatment of acquired and inherited …

Photoresponsive biomaterials for targeted drug delivery and 4D cell culture

ER Ruskowitz, CA DeForest - Nature Reviews Materials, 2018 - nature.com
Biological signalling is regulated through a complex and tightly choreographed interplay
between cells and their extracellular matrix. The spatiotemporal control of these interactions …

Recent advances in subcellular targeted cancer therapy based on functional materials

WH Chen, GF Luo, XZ Zhang - Advanced Materials, 2019 - Wiley Online Library
Recently, diverse functional materials that take subcellular structures as therapeutic targets
are playing increasingly important roles in cancer therapy. Here, particular emphasis is …

Photoactivatable silencing extracellular vesicle (PASEV) sensitizes cancer immunotherapy

M Lu, H Xing, W Shao, T Zhang, M Zhang… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has delivered impressive outcomes in combating tumor malignancies.
However, insufficient immune infiltration and poor immunogenicity within the tumor …

Photodynamic efficiency: from molecular photochemistry to cell death

IOL Bacellar, TM Tsubone, C Pavani… - International journal of …, 2015 - mdpi.com
Photodynamic therapy (PDT) is a clinical modality used to treat cancer and infectious
diseases. The main agent is the photosensitizer (PS), which is excited by light and converted …

Non-viral delivery of nucleic acids: insight into mechanisms of overcoming intracellular barriers

M Durymanov, J Reineke - Frontiers in pharmacology, 2018 - frontiersin.org
Delivery of genes, including plasmid DNAs, short interfering RNAs (siRNAs), and
messenger RNAs (mRNAs), using artificial non-viral nanotherapeutics is a promising …

Intracellular delivery of nanomaterials: how to catch endosomal escape in the act

TF Martens, K Remaut, J Demeester, SC De Smedt… - Nano Today, 2014 - Elsevier
Successful cytosolic delivery of nanomaterials is becoming more and more important, given
the increase in intracellular applications of quantum dots, gold nanoparticles, liposomal drug …

Co-delivery of bee venom melittin and a photosensitizer with an organic–inorganic hybrid nanocarrier for photodynamic therapy and immunotherapy

H Liu, Y Hu, Y Sun, C Wan, Z Zhang, X Dai, Z Lin… - ACS …, 2019 - ACS Publications
Photodynamic therapy (PDT) is a clinical cancer treatment modality based on the induction
of therapeutic reactive oxygen species (ROS), which can trigger immunogenic cell death …