Deep eutectic solvents enhancing drug solubility and its delivery

A Sharma, YR Park, A Garg, BS Lee - Journal of Medicinal …, 2024 - ACS Publications
Deep eutectic solvents (DES) are environmentally friendly solvents with the potential to
dissolve bioactive compounds without affecting their characteristics. DES has special …

An insight into pharmaceutical challenges with ionic liquids: where do we stand in transdermal delivery?

A Jain, AK Shakya, SK Prajapati… - … in Bioengineering and …, 2024 - frontiersin.org
Ionic liquids (ILs) represent an exciting and promising solution for advancing drug delivery
platforms. Their unique properties, including broad chemical diversity, adaptable structures …

Tuning Ferulic Acid Solubility in Choline-Chloride-and Betaine-Based Deep Eutectic Solvents: Experimental Determination and Machine Learning Modeling

T Jeliński, M Przybyłek, R Różalski, K Romanek… - …, 2024 - pmc.ncbi.nlm.nih.gov
Deep eutectic solvents (DES) represent a promising class of green solvents, offering
particular utility in the extraction and development of new formulations of natural compounds …

Strategies to Prepare Chitin and Chitosan-Based Bioactive Structures Aided by Deep Eutectic Solvents: A Review

DA Durante-Salmerón, I Fraile-Gutiérrez… - Catalysts, 2024 - mdpi.com
Chitin and chitosan, abundant biopolymers derived from the shells of crustaceans and the
cell walls of fungi, have garnered considerable attention in pharmaceutical circles due to …

[HTML][HTML] Exploration of the Solubility Hyperspace of Selected Active Pharmaceutical Ingredients in Choline-and Betaine-Based Deep Eutectic Solvents: Machine …

P Cysewski, T Jeliński, M Przybyłek - Molecules, 2024 - mdpi.com
Deep eutectic solvents (DESs) are popular green media used for various industrial,
pharmaceutical, and biomedical applications. However, the possible compositions of …

[HTML][HTML] Thermophysical characterization of lidocaine: camphor: thymol or l-menthol eutectic mixtures: Experimental and modelling

M Sancho-Blasco, JL Pastor, J Muñoz-Embid… - Journal of Molecular …, 2025 - Elsevier
Knowing the values of the thermodynamic and transport properties of fluids is essential for
their implementation in different fields. In addition, their analysis allows us to understand the …

Experimental and Machine-Learning-Assisted Design of Pharmaceutically Acceptable Deep Eutectic Solvents for the Solubility Improvement of Non-Selective COX …

P Cysewski, T Jeliński, M Przybyłek, A Mai, J Kułak - Molecules, 2024 - mdpi.com
Deep eutectic solvents (DESs) are commonly used in pharmaceutical applications as
excellent solubilizers of active substances. This study investigated the tuning of ibuprofen …

Eutectic Mixtures of APIs: A way to Improve the Physiochemical Properties and Oral Bioavailability of the Drugs

MB Singh, U Sharma, AP Singh Raman@… - …, 2024 - Wiley Online Library
Eutectic mixtures (EMs) are consisted of two or more components with a specific
composition and melting point, have received a lot of attention in pharmaceutical research …