Clinical significance of measuring serum cytokine levels as inflammatory biomarkers in adult and pediatric COVID-19 cases: A review

BM Liu, TB Martins, LK Peterson, HR Hill - Cytokine, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a rapidly evolving infectious/inflammatory
disorder which has turned into a global pandemic. With severe acute respiratory syndrome …

Blood biomarkers in ischemic stroke: potential role and challenges in clinical practice and research

K Makris, A Haliassos, M Chondrogianni… - Critical reviews in …, 2018 - Taylor & Francis
Fast and accurate diagnosis of stroke is crucial for the immediate application of the right
therapy to patients. However, rapid diagnosis is still a challenge since an ischemic stroke …

[HTML][HTML] Determinants of early antibody responses to COVID-19 mRNA vaccines in a cohort of exposed and naïve healthcare workers

G Moncunill, R Aguilar, M Ribes, N Ortega, R Rubio… - …, 2022 - thelancet.com
Background Two doses of mRNA vaccination have shown> 94% efficacy at preventing
COVID-19 mostly in naïve adults, but it is not clear if the second dose is needed to maximize …

[HTML][HTML] Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays

W De Jager, K Bourcier, GT Rijkers, BJ Prakken… - BMC immunology, 2009 - Springer
Background Growing knowledge about cellular interactions in the immune system, including
the central role of cytokine networks, has lead to new treatments using monoclonal …

Suppression of non-specific binding in serological Luminex assays

T Waterboer, P Sehr, M Pawlita - Journal of immunological methods, 2006 - Elsevier
Bead-based suspension array technology (xMAP, Luminex Corp.) permits the simultaneous
analysis of antibodies with specificities for up to 100 different antigens in a single reaction …

Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies

W de Jager, BJ Prakken, JWJ Bijlsma, W Kuis… - Journal of …, 2005 - Elsevier
Cytokines, chemokines and soluble adhesion molecules interact in a complex network
within the immune system. Fingerprinting of these proteins may allow the use of these …

Analysis of proinflammatory and anti-inflammatory cytokine serum concentrations in patients with multiple sclerosis by using a multiplexed immunoassay

TB Martins, JW Rose, TD Jaskowski… - American journal of …, 2011 - academic.oup.com
We examined cytokines and other inflammatory markers in serum samples from 833 patients
with multiple sclerosis and 117 healthy control subjects. A multiplexed immunoassay was …

Weight loss larger than 10% is needed for general improvement of levels of circulating adiponectin and markers of inflammation in obese subjects: a 3-year weight …

EL Madsen, A Rissanen, JM Bruun… - European Journal of …, 2008 - academic.oup.com
Objective To investigate the effects of: I) short-(8 weeks), II) long-term (3 years) weight loss,
and III) the degree of weight loss on circulating levels of adiponectin, high sensitive-C …

Effects of serum and plasma matrices on multiplex immunoassays

Y Rosenberg-Hasson, L Hansmann, M Liedtke… - Immunologic …, 2014 - Springer
Multiplexed fluorescence or electrochemiluminescence immunoassays of soluble cytokines
are commonly performed in the context of human serum or plasma, to look for disease …

[HTML][HTML] An evaluation of commercial fluorescent bead-based luminex cytokine assays

JF Djoba Siawaya, T Roberts, C Babb, G Black… - PloS one, 2008 - journals.plos.org
The recent introduction of fluorescent bead-based technology, allowing the measurement of
multiples analytes in a single 25–50 µl sample has revolutionized the study of cytokine …