Regulatory T (Treg) cells are essential for immunological tolerance and homeostasis.
Although forkhead box (Fox) p3 is continually required to reinforce the Treg cell program …

Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Infection with the malaria parasite, Plasmodium, is characterized by excessive inflammation.
The establishment of a precise balance between the pro-and anti-inflammatory responses is …

Malaria, caused by the protozoan Plasmodium, is a devastating mosquito-borne disease
with the potential to affect nearly half the world's population. Despite mounting substantial T …

Parasite burden predicts disease severity in malaria and risk of death in cerebral malaria
patients. In murine experimental cerebral malaria (ECM), parasite burden and CD8+ T cells …

Regulatory T cells (Tregs) play a cardinal role in the immune system by suppressing
detrimental autoimmune responses, but their role in acute, chronic infectious diseases and …

Cerebral malaria (CM) is a complex parasitic disease caused by Plasmodium sp. Failure to
establish an appropriate balance between pro-and anti-inflammatory immune responses is …

Infectious agents have intimately co-evolved with the host immune system, acquiring a
portfolio of highly sophisticated mechanisms to modulate immunity. Among the common …

Long-term organ transplant survival remains suboptimal, and life-long immunosuppression
predisposes transplant recipients to an increased risk of infection, malignancy, and kidney …

Gastrointestinal symptoms, such as abdominal pain and diarrhea, are frequently observed in
patients with Plasmodium falciparum malaria. However, the correlation between malaria …