Tissue immunometabolism: development, physiology, and pathobiology

K Man, VI Kutyavin, A Chawla - Cell metabolism, 2017 - cell.com
Evolution of metazoans resulted in the specialization of cellular and tissue function. This was
accomplished by division of labor, which allowed tissue parenchymal cells to prioritize their …

Beyond energy balance regulation: The underestimated role of adipose tissues in host defense against pathogens

J Barthelemy, G Bogard, I Wolowczuk - Frontiers in Immunology, 2023 - frontiersin.org
Although the adipose tissue (AT) is a central metabolic organ in the regulation of whole-
body energy homeostasis, it is also an important endocrine and immunological organ. As an …

The immune response in adipocytes and their susceptibility to infection: a possible relationship with infectobesity

O López-Ortega, NC Moreno-Corona… - International Journal of …, 2022 - mdpi.com
The current obesity pandemic has been expanding in both developing and developed
countries. This suggests that the factors contributing to this condition need to be …

Increased risk of incident diabetes among individuals with latent tuberculosis infection

MJ Magee, A Khakharia, NR Gandhi, CL Day… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE In cross-sectional US studies, patients with diabetes had twice the prevalence
of latent tuberculosis infection (LTBI) compared with those without diabetes. However …

Triacylglycerols: Fuelling the Hibernating Mycobacterium tuberculosis

RK Maurya, S Bharti, MY Krishnan - Frontiers in cellular and infection …, 2019 - frontiersin.org
Mycobacterium tuberculosis (Mtb) has the remarkable ability to persist with a modified
metabolic status and phenotypic drug tolerance for long periods in the host without …

The relevance of persisters in tuberculosis drug discovery

S Mandal, S Njikan, A Kumar, JV Early… - …, 2019 - microbiologyresearch.org
Bacterial persisters are a subpopulation of cells that exhibit phenotypic resistance during
exposure to a lethal dose of antibiotics. They are difficult to target and thought to contribute …

Pathogenesis of post primary tuberculosis: immunity and hypersensitivity in the development of cavities

RL Hunter, JK Actor, SA Hwang… - Annals of Clinical & …, 2014 - Assoc Clin Scientists
M. Tuberculosis (MTB) is an obligate human parasite even though humans are more
resistant than any of the animals used for study. It is a human parasite because only humans …

HIV persistence in adipose tissue reservoirs

J Couturier, DE Lewis - Current HIV/AIDS Reports, 2018 - Springer
Abstract Purpose of Review The purpose of this review is to examine the evidence
describing adipose tissue as a reservoir for HIV-1 and how this often expansive anatomic …

Convergence of non-communicable diseases and tuberculosis: a two-way street?

MJ Magee, AD Salindri, UP Gujral… - … of Tuberculosis and …, 2018 - ingentaconnect.com
The intersection of tuberculosis (TB) with non-communicable diseases (NCDs), including
diabetes mellitus (DM), chronic lung disease (CLD), and cardiovascular disease (CVD), has …

Experimental models of foamy macrophages and approaches for dissecting the mechanisms of lipid accumulation and consumption during dormancy and reactivation …

P Santucci, F Bouzid, N Smichi, I Poncin… - Frontiers in cellular …, 2016 - frontiersin.org
Despite a slight decline since 2014, tuberculosis (TB) remains the major deadly infectious
disease worldwide with about 1.5 million deaths each year and with about one-third of the …