Due to the diverse mechanisms of action of antiseizure drugs, there has been a rise in
prescriptions of these drugs for non-epileptic pathologies. One drug that is now being used …

Background Influenced by several trials and reviews highlighting positive outcomes,
topiramate is increasingly prescribed as a treatment for alcohol use disorders (AUD s). The …

Abstract Elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA, Trikafta) is the newest Cystic Fibrosis
Transmembrane Conductance Regulator (CFTR) modulator drug approved by the Food and …

Background: The current paper includes a systematic search of the literature, a detailed
presentation of the results, and a grading of treatment options in terms of efficacy and …

The current statement is a systematic review of the available data concerning the efficacy of
medication treatment of bipolar disorder (BP). A systematic MEDLINE search was made …

This paper is a systematic review of the available data concerning the treatment of bipolar
disorder: a systematic Medline search concerning treatment guidelines and clinical trials …

Objective: To evaluate the efficacy and tolerability of adjunctive topiramate compared to
placebo in reducing weight and binge eating in obese patients with binge-eating disorder …

Alcohol use disorder (AUD), as currently defined in the Diagnostic and Statistical Manual,
5th Edition (DSM–5), is a heterogeneous disorder stemming from a complex interaction of …

Increasing evidence suggests that abnormalities in amino neurotransmission are associated
with the neurobiology of depression. Preclinical studies demonstrate that GABA modulating …

The prevalence of pediatric obesity has increased exponentially over the past four decades.
The American Academy of Pediatrics recently released updated clinical practice guidelines …