Polycystic ovary syndrome

AE Joham, RJ Norman, E Stener-Victorin… - The lancet Diabetes & …, 2022 - thelancet.com
Polycystic ovary syndrome (PCOS) affects 5–18% of women, and is a reproductive,
metabolic, and psychological condition with impacts across the lifespan. The cause is …

[HTML][HTML] Metformin: Is it a drug for all reasons and diseases?

CR Triggle, I Mohammed, K Bshesh, I Marei, K Ye… - Metabolism, 2022 - Elsevier
Metformin was first used to treat type 2 diabetes in the late 1950s and in 2022 remains the
first-choice drug used daily by approximately 150 million people. An accumulation of …

Update on PCOS: consequences, challenges, and guiding treatment

KM Hoeger, A Dokras, T Piltonen - The Journal of Clinical …, 2021 - academic.oup.com
Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrine
disorders in women and despite this, diagnostic challenges, delayed diagnosis, and less …

Oxidative stress in oocyte aging and female reproduction

L Wang, J Tang, L Wang, F Tan, H Song… - Journal of cellular …, 2021 - Wiley Online Library
In a healthy body, reactive oxygen species (ROS) and antioxidants remain balanced. When
the balance is broken toward an overabundance of ROS, oxidative stress appears and may …

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

M Foretz, B Guigas, B Viollet - Nature Reviews Endocrinology, 2019 - nature.com
Despite its position as the first-line drug for treatment of type 2 diabetes mellitus, the
mechanisms underlying the plasma glucose level-lowering effects of metformin (1, 1 …

Polycystic ovary syndrome: pathophysiology, presentation, and treatment with emphasis on adolescent girls

SF Witchel, SE Oberfield, AS Peña - Journal of the Endocrine …, 2019 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by
hyperandrogenism and chronic anovulation. Depending on diagnostic criteria, 6% to 20% of …

Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment

HF Escobar-Morreale - Nature Reviews Endocrinology, 2018 - nature.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic
disorders in premenopausal women. Heterogeneous by nature, PCOS is defined by a …

Lifestyle management in polycystic ovary syndrome–beyond diet and physical activity

S Cowan, S Lim, C Alycia, S Pirotta, R Thomson… - BMC endocrine …, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a common condition affecting reproductive-aged
women with reproductive, metabolic and psychological consequences. Weight and lifestyle …

Association of gestational weight gain with maternal and infant outcomes: a systematic review and meta-analysis

RF Goldstein, SK Abell, S Ranasinha, M Misso… - Jama, 2017 - jamanetwork.com
Importance Body mass index (BMI) and gestational weight gain are increasing globally. In
2009, the Institute of Medicine (IOM) provided specific recommendations regarding the ideal …

Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy

S Patel - The Journal of steroid biochemistry and molecular …, 2018 - Elsevier
Polycystic ovary syndrome (PCOS) is an endocrine disorder, afflicting females of
reproductive age. This syndrome leads to infertility, insulin resistance, obesity, and …