RNA contributions to the form and function of biomolecular condensates

C Roden, AS Gladfelter - Nature Reviews Molecular Cell Biology, 2021 - nature.com
Biomolecular condensation partitions cellular contents and has important roles in stress
responses, maintaining homeostasis, development and disease. Many nuclear and …

Prediction of RNA secondary structure by free energy minimization

DH Mathews, DH Turner - Current opinion in structural biology, 2006 - Elsevier
RNA secondary structure is often predicted from sequence by free energy minimization.
Over the past two years, advances have been made in the estimation of folding free energy …

Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

NC Huston, H Wan, MS Strine, RCA Tavares, CB Wilen… - Molecular cell, 2021 - cell.com
Summary Severe-acute-respiratory-syndrome-related coronavirus 2 (SARS-CoV-2) is the
positive-sense RNA virus that causes coronavirus disease 2019 (COVID-19). The genome …

ViennaRNA Package 2.0

R Lorenz, SH Bernhart… - Algorithms for molecular …, 2011 - Springer
Background Secondary structure forms an important intermediate level of description of
nucleic acids that encapsulates the dominating part of the folding energy, is often well …

The vienna RNA websuite

AR Gruber, R Lorenz, SH Bernhart… - Nucleic acids …, 2008 - academic.oup.com
Abstract The Vienna RNA Websuite is a comprehensive collection of tools for folding, design
and analysis of RNA sequences. It provides a web interface to the most commonly used …

In vivo reconstitution finds multivalent RNA–RNA interactions as drivers of mesh-like condensates

W Ma, G Zhen, W Xie, C Mayr - Elife, 2021 - elifesciences.org
Liquid-like condensates have been thought to be sphere-like. Recently, various
condensates with filamentous morphology have been observed in cells. One such …

RNAstructure: software for RNA secondary structure prediction and analysis

JS Reuter, DH Mathews - BMC bioinformatics, 2010 - Springer
Background To understand an RNA sequence's mechanism of action, the structure must be
known. Furthermore, target RNA structure is an important consideration in the design of …

A unified dynamic programming framework for the analysis of interacting nucleic acid strands: enhanced models, scalability, and speed

ME Fornace, NJ Porubsky, NA Pierce - ACS Synthetic Biology, 2020 - ACS Publications
Dynamic programming algorithms within the NUPACK software suite enable analysis of
nucleic acid sequences over complex and test tube ensembles containing arbitrary numbers …

Disease-associated mutations that alter the RNA structural ensemble

M Halvorsen, JS Martin, S Broadaway… - PLoS genetics, 2010 - journals.plos.org
Genome-wide association studies (GWAS) often identify disease-associated mutations in
intergenic and non-coding regions of the genome. Given the high percentage of the human …

The Nucleic Acid Database: new features and capabilities

B Coimbatore Narayanan, J Westbrook… - Nucleic acids …, 2014 - academic.oup.com
Abstract The Nucleic Acid Database (NDB)(http://ndbserver. rutgers. edu) is a web portal
providing access to information about 3D nucleic acid structures and their complexes. In …