Apolipoprotein E and Alzheimer's disease: findings, hypotheses, and potential mechanisms

N Koutsodendris, MR Nelson, A Rao… - Annual Review of …, 2022 - annualreviews.org
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder that involves
dysregulation of many cellular and molecular processes. It is notoriously difficult to develop …

Cognitive neuroscience of attention deficit hyperactivity disorder (ADHD) and its clinical translation

K Rubia - Frontiers in human neuroscience, 2018 - frontiersin.org
This review focuses on the cognitive neuroscience of Attention Deficit Hyperactivity Disorder
(ADHD) based on functional magnetic resonance imaging (fMRI) studies and on recent …

An improved neuroanatomical model of the default-mode network reconciles previous neuroimaging and neuropathological findings

PN Alves, C Foulon, V Karolis, D Bzdok… - Communications …, 2019 - nature.com
The brain is constituted of multiple networks of functionally correlated brain areas, out of
which the default-mode network (DMN) is the largest. Most existing research into the DMN …

Situating the default-mode network along a principal gradient of macroscale cortical organization

DS Margulies, SS Ghosh, A Goulas… - Proceedings of the …, 2016 - National Acad Sciences
Understanding how the structure of cognition arises from the topographical organization of
the cortex is a primary goal in neuroscience. Previous work has described local functional …

[HTML][HTML] Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms

RL Carhart-Harris, L Roseman, M Bolstridge… - Scientific reports, 2017 - nature.com
Psilocybin with psychological support is showing promise as a treatment model in psychiatry
but its therapeutic mechanisms are poorly understood. Here, cerebral blood flow (CBF) and …

The default network and self‐generated thought: Component processes, dynamic control, and clinical relevance

JR Andrews‐Hanna, J Smallwood… - Annals of the new York …, 2014 - Wiley Online Library
Though only a decade has elapsed since the default network (DN) was first defined as a
large‐scale brain system, recent years have brought great insight into the network's adaptive …

The role of the posterior cingulate cortex in cognition and disease

R Leech, DJ Sharp - Brain, 2014 - academic.oup.com
The posterior cingulate cortex is a highly connected and metabolically active brain region.
Recent studies suggest it has an important cognitive role, although there is no consensus …

Resting-state functional connectivity in autism spectrum disorders: a review

JV Hull, LB Dokovna, ZJ Jacokes… - Frontiers in …, 2017 - frontiersin.org
Ongoing debate exists within the resting-state functional MRI (fMRI) literature over how
intrinsic connectivity is altered in the autistic brain, with reports of general over-connectivity …

Influences on the test–retest reliability of functional connectivity MRI and its relationship with behavioral utility

S Noble, MN Spann, F Tokoglu, X Shen… - Cerebral …, 2017 - academic.oup.com
Best practices are currently being developed for the acquisition and processing of resting-
state magnetic resonance imaging data used to estimate brain functional organization—or …

Self-awareness, self-regulation, and self-transcendence (S-ART): a framework for understanding the neurobiological mechanisms of mindfulness

DR Vago, DA Silbersweig - Frontiers in human neuroscience, 2012 - frontiersin.org
Mindfulness—as a state, trait, process, type of meditation, and intervention has proven to be
beneficial across a diverse group of psychological disorders as well as for general stress …