Introduction Myeloproliferative neoplasm (MPN) is a heterogeneous group of hematopoietic
stem cell disorders characterized by clonal proliferation of one of more of the hematopoietic …

Primary myelofibrosis is a chronic clonal stem cell disorder that results in a build-up of
marrow fibrosis and dysfunction, hypermetabolic states, and myeloid metaplasia. The …

Normal marrow contains both hematopoietic/red and fatty/yellow marrow with a predictable
pattern of conversion and skeletal distribution on MRI. Many variations in normal bone …

The complementarity and the competitiveness of liquid biomarkers, histopathology and
imaging features as well as the consequences of digitalization and automation on image …

Introduction The identification of specific molecular signatures and the development of new
targeted drugs have changed the paradigm of onco-nephrology, now allowing a multiscale …

Aims Spleen and liver stiffness, investigated by VCTE (Vibration-Controlled Transient
Elastography), have been associated with marrow fibrosis in patients with myeloproliferative …

Gastrointestinal bleeding (GIB) among cancer patients is a major source of morbidity and
mortality. Although a wide variety of etiologies contribute to GIB, special considerations …

Introduction: Somatic mutations in the calreticulin (CALR) gene occur in most
myeloproliferative neoplasm (MPN) patients who lack Janus kinase 2 or thrombopoietin …

Myelofibrosis is a BCR-ABL1-negative chronic myeloproliferative neoplasm that includes
primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential …

The growing expectancy of life is one of the main contributors for the increasing number of
older patients with hematologic malignancies. Geriatric patients with myeloid and lymphoid …