There have been some modest recent advancements in the research of Complex Regional
Pain Syndrome, yet the amount and quality of the work in this complicated multifactorial …

The upcoming 11th revision of the International Statistical Classification of Diseases and
Related Health Problems (ICD) of the World Health Organization (WHO) offers a unique …

Background Up-regulation of hepatic delta-aminolevulinic acid synthase 1 (ALAS1), with
resultant accumulation of delta-aminolevulinic acid (ALA) and porphobilinogen, is central to …

Over the past decade there has been an increasing reliance on strong opioids to treat acute
and chronic pain, which has been associated with a rising epidemic of prescription opioid …

Neuropathic pain remains a significant unmet medical need. Several recommendations
have recently been proposed concerning pharmacotherapy, neurostimulation techniques …

Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …

Thoracic neuropathic pain is a debilitating condition that is often poorly responsive to oral
and topical pharmacotherapy. The benefit of interventional nerve block procedures is …

Pain is common in cancer patients, particularly in the advanced stage of disease when the
prevalence is estimated to be more than 70%[1], contributing to poor physical and emotional …

Background This review is one of a series on drugs used to treat chronic neuropathic pain.
Estimates of the population prevalence of chronic pain with neuropathic components range …

Background This review updates part of an earlier Cochrane Review titled" Pregabalin for
acute and chronic pain in adults", and considers only neuropathic pain (pain from damage to …