Most pathogens initiate their infections at the human mucosal surface. Therefore, mucosal
vaccination, especially through oral or intranasal administration routes, is highly desired for …

This review summarizes current knowledge on the structure, function, assembly and
biomedical applications of the superfamily of adhesive fimbrial organelles exposed on the …

The design of biodegradable polymeric delivery systems based on polyanhydrides that
would provide for improved structural integrity of Yersinia pestis antigens was the main goal …

This review summarizes the current knowledge on the structure, function, assembly, and
biomedical applications of the family of adhesive fimbrial organelles assembled on the …

The recent progress in immunoinformatics provided the basis for an accelerated
development of target-specific peptide vaccines as an alternative to the traditional vaccine …

Plague, which is caused by Yersinia pestis, is one of the most dangerous infectious
diseases. No FDA-approved vaccine against plague is available for human use at present …

Bacillus anthracis is the etiological agent of anthrax. Protective antigen (PA) has been
established as the key protective immunogen and is the major component of anthrax …

Although multi-epitope vaccines have been evaluated for various diseases, they have not
yet been investigated for lymphatic filariasis. Here, we report for the first time identification of …

Defensins display immunostimulatory activities including a chemotactic effect for T
lymphocytes/immature dendritic cells and secretion of pro-inflammatory cytokines suggest …

In this study, a new subunit vaccine that comprised native F1 and recombinant rV270 was
evaluated for protective efficacy using mouse, guinea pig and rabbit models in comparison …