Cancer stem cells (CSCs) are a subpopulation of tumour cells that possess the stem cell
properties of self-renewal and differentiation. Stem cells might be the target cells responsible …

Objective: The genus Ferula L. includes perennial flowering plants belonging to the
Apiaceae family. This genus is a rich source of biologically active phytochemicals such as …

Background Oxidative stress is a significant feature in the pathomechanism of
neurodegenerative diseases. Thus, the search for an effective and safe novel antioxidant …

Ancient physicians frequently used the resin of Ferula species to treat cancer. Today, some
folkloric recipes used for cancer treatment also contain the resin of Ferula species. The …

Background Ferula species are reputed in folk medicine for the treatment of a variety of
disorders. There have been sporadic reports on the chemopreventive and chemosensitizing …

Polymeric micelles produced from amphiphilic copolymers, are considered promising drug
delivery platforms. Because of their ability to co-deliver hydrophilic (Dox) and hydrophobic …

In the present study, fifteen sesquiterpene coumarins were isolated and purified from
different Ferula species, and were tested for their MDR reversal properties. Enhancement of …

Background Cancer is one of the leading causes of death worldwide, both in developed and
developing countries. Of note, colorectal adenoma encompasses a high rate of …

Background: Nerolidol (NER) is a sesquiterpene alcohol with various biological and
pharmacological activities, especially antitumor effects against different cancer models. The …

Background: Prostate cancer is one of the leading causes of cancer related deaths in males
worldwide. Overexpression of 15-lipoxygenase-1 (15-LOX-1) enzyme and high activity of its …