Metal complexes of quinolone antibiotics and their applications: an update

V Uivarosi - Molecules, 2013 - mdpi.com
Quinolones are synthetic broad-spectrum antibiotics with good oral absorption and excellent
bioavailability. Due to the chemical functions found on their nucleus (a carboxylic acid …

The interactions of metal ions with quinolone antibacterial agents

I Turel - Coordination Chemistry Reviews, 2002 - Elsevier
The quinolones are a group of synthetic antibacterial agents structurally related to nalidixic
acid. The absorption of quinolone drugs is lowered when they are consumed simultaneously …

Current and potential applications of bismuth-based drugs

DM Keogan, DM Griffith - Molecules, 2014 - mdpi.com
Bismuth compounds have been used extensively as medicines and in particular for the
treatment of gastrointestinal ailments. In addition to bismuth's well known gastroprotective …

Structure and function of “metalloantibiotics”

LJ Ming - Medicinal Research Reviews, 2003 - Wiley Online Library
Although most antibiotics do not need metal ions for their biological activities, there are a
number of antibiotics that require metal ions to function properly, such as bleomycin (BLM) …

Interactions of metal ions with two quinolone antimicrobial agents (cinoxacin and ciprofloxacin): Spectroscopic and X-ray structural characterization. Antibacterial …

MP Lopez-Gresa, R Ortiz, L Perelló, J Latorre… - Journal of inorganic …, 2002 - Elsevier
Several novel metal–quinolone compounds have been synthesized and characterized by
analytical, spectroscopic and X-ray diffraction methods. The crystal structure of the four …

Synthesis, DFT calculation, pharmacological evaluation, and catalytic application in the synthesis of diverse pyrano [2, 3-c] pyrazole derivatives

MMK Amer, MH Abdellattif, SM Mouneir, WA Zordok… - Bioorganic …, 2021 - Elsevier
Pyranopyrazole and its derivatives are classified to be a pharmacologically significant active
scaffold for almost all modes of biological activities. In this work, An efficient, green, and …

Novel Copper(II) Complex of N-Propyl-norfloxacin and 1,10-Phenanthroline with Enhanced Antileukemic and DNA Nuclease Activities

ME Katsarou, EK Efthimiadou, G Psomas… - Journal of medicinal …, 2008 - ACS Publications
We have synthesized and characterized a novel copper (II) complex of the fluoroquinolone
antibacterial drug N-propyl-norfloxacin (Hpr-norf) in the presence of 1, 10-phenanthroline …

Synthesis and characterization of norfloxacin-transition metal complexes (group 11, IB): spectroscopic, thermal, kinetic measurements and biological activity

MS Refat - Spectrochimica Acta Part A: Molecular and …, 2007 - Elsevier
The investigation of the new structures of Ag (I), Cu (II) and Au (III) complexes,[Ag2 (Nor)
2](NO3) 2,[Cu (Nor) 2 (H2O) 2] SO4· 5H2O and [Au (Nor) 2 (H2O) 2] Cl3 (where, Nor …

Structure and biological properties of the copper (II) complex with the quinolone antibacterial drug N-propyl-norfloxacin and 2, 2′-bipyridine

EK Efthimiadou, H Thomadaki, Y Sanakis… - Journal of inorganic …, 2007 - Elsevier
The neutral mononuclear copper complex with the quinolone antibacterial drug N-propyl-
protected norfloxacin, Hpr-norfloxacin, in the presence of the nitrogen donor heterocyclic …

Synthesis, in silico prediction and in vitro evaluation of antimicrobial activity, dft calculation and theoretical investigation of novel xanthines and uracil containing …

S El-Kalyoubi, F Agili, WA Zordok… - International Journal of …, 2021 - mdpi.com
Novel xanthine and imidazolone derivatives were synthesized based on oxazolone
derivatives 2a-c as a key intermediate. The corresponding xanthine 3-5 and imidazolone …