Purpose We report our experience disrupting the blood-brain barrier (BBB) to improve drug
delivery in glioblastoma patients receiving temozolomide chemotherapy. The goals of this …

Abstract Background and Objectives The influence of the intracranial pressure field must be
discussed with the development of a single-element transducer for low-intensity transcranial …

Transcranial focused ultrasound ablation has emerged as a promising technique for treating
neurological disorders. The clinical system exclusively employed the ray tracing method to …

In this paper, we utilize micro-computed tomography (micro-CT) to obtain micro-CT images
with a resolution of 60 μm and establish a micro-CT model based on the k-wave toolbox …

Background The generation of transcranial ultrasound is usually based on the piezoelectric
effect, so it is necessary to attach transducers around the skull. However, the skull will cause …

Transcranial ultrasound applications require accurate simulations to predict intracranial
acoustic pressure fields. The current gold standard typically consists of calculating a …

Transcranial focused ultrasound has emerged as a promising and innovative
neuromodulation technique 29 with the potential to foster brain disease therapies. Its …