Electrophysiological research on mGluRs is now very extensive, and it is clear that activation
of mGluRs results in a large number of diverse cellular actions. Studies of mGluRs and on …

In this review we take a physiological perspective on the role of voltage‐gated potassium
channels in an identified neuron in the auditory brainstem. The large number of KCN genes …

Pain after nerve damage is an expression of pathological operation of the nervous system,,
one hallmark of which is tactile allodynia—pain hypersensitivity evoked by innocuous …

Measles virus continues to be a major killer of children, claiming roughly one million lives a
year. Measles virus infection causes profound immunosuppression, which makes measles …

Calcium-triggered fusion of synaptic vesicles and neurotransmitter release are fundamental
signalling steps in the central nervous system. It is generally assumed that fast transmitter …

The size of a pool of readily releasable vesicles at a giant brainstem synapse, the calyx of
Held, was probed with three independent approaches. Using simultaneous pre-and …

Synapses in the central nervous system undergo various short-and long-term changes in
their strength,,, but it is often difficult to distinguish whether presynaptic or postsynaptic …

Synapses show widely varying degrees of short-term facilitation and depression. Several
mechanisms have been proposed to underlie short-term plasticity, but the contributions of …

Impulses in primary afferent nerve fibers may produce short-or long-lasting modifications in
spinal nociception. Here we have identified a robust long-term depression (LTD) of synaptic …

Voltage-gated calcium channels are well characterized at neuronal somata but less
thoroughly understood at the presynaptic terminal where they trigger transmitter release. In …