Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

The calibrated application of limited-duration, cyclic, moderately intense hypoxia-
reoxygenation increases cardiac resistance to ischemia-reperfusion stress. These …

Intermittent hypoxia (IH) has been extensively studied during the last decade, primarily as a
surrogate model of sleep apnea. However, IH is a much more pervasive phenomenon in …

The ability to sense and respond to oxygen deprivation is required for survival; thus,
understanding the mechanisms by which changes in oxygen are linked to cell viability and …

It has been documented that reactive oxygen species (ROS) contribute to oxidative stress,
leading to diseases such as ischemic heart disease. Recently, increasing evidence has …

Since a constant supply of oxygen is essential to sustain life, organisms have evolved
multiple defence mechanisms to ensure maintenance of the delicate balance between …

This review deals with the capability of the heart to adapt to chronic hypoxia in animals
exposed to either natural or simulated high altitude. From the broad spectrum of related …

The misbehaving attitude of Ca 2+ signaling pathways could be the probable reason in
many muscular disorders such as myopathies, systemic disorders like hypoxia, sepsis …

Enhanced reactive oxygen species (ROS) at the beginning of reperfusion activated signal
transducer and activator of transcription 3 (STAT3) in intermittent hypobaric hypoxia (IHH) …

Pretreatment of berbamine protects the heart from ischemia/reperfusion (I/R) injury. However
it is unknown whether it has cardioprotection when given at the onset of reperfusion …