New approaches to sepsis: molecular diagnostics and biomarkers

K Reinhart, M Bauer, NC Riedemann… - Clinical microbiology …, 2012 - Am Soc Microbiol
Sepsis is among the most common causes of death in hospitals. It arises from the host
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …

Biomarkers of inflammation and the etiology of sepsis

I Grondman, A Pirvu, A Riza, M Ioana… - Biochemical Society …, 2020 - portlandpress.com
Sepsis is characterized as a life-threatening organ dysfunction syndrome that is caused by a
dysregulated host response to infection. The main etiological causes of sepsis are bacterial …

Neutrophil-to-lymphocyte ratio, past, present and future perspectives

R Zahorec - Bratisl Lek Listy, 2021 - search.ebscohost.com
In the review we analyzed short history of the establishment of a novel hematological
parameter for systemic inflammation and stress coined as a neutrophil to lymphocyte ratio …

The neutrophil-lymphocyte count ratio in patients with community-acquired pneumonia

CPC de Jager, PC Wever, EFA Gemen, R Kusters… - 2012 - journals.plos.org
Study Objective The neutrophil-lymphocyte count ratio (NLCR) has been identified as a
predictor of bacteremia in medical emergencies. The aim of this study was to investigate the …

Interleukins profiling for biosensing applications: possibilities and the future of disease detection

S Shekhar, AK Yadav, A Khosla, PR Solanki - ECS Sensors Plus, 2022 - iopscience.iop.org
Interleukins (ILs) are a major subclass of cytokines acting as molecular messengers playing
role in immune system responses via a cascade of signaling pathways. Belonging to the …

Procalcitonin as a diagnostic marker and IL-6 as a prognostic marker for sepsis

DW Jekarl, SY Lee, J Lee, YJ Park, Y Kim… - … and infectious disease, 2013 - Elsevier
The diagnosis and prognosis of sepsis after antimicrobial therapy among systemic
inflammatory response syndrome (SIRS) patients were evaluated with the biomarkers …

Host biomarkers for distinguishing bacterial from non-bacterial causes of acute febrile illness: a comprehensive review

AJ Kapasi, S Dittrich, IJ González, TC Rodwell - PloS one, 2016 - journals.plos.org
Background In resource limited settings acute febrile illnesses are often treated empirically
due to a lack of reliable, rapid point-of-care diagnostics. This contributes to the …

Effectiveness and safety of procalcitonin evaluation for reducing mortality in adults with sepsis, severe sepsis or septic shock

BNG Andriolo, RB Andriolo… - Cochrane Database …, 2017 - cochranelibrary.com
Background Serum procalcitonin (PCT) evaluation has been proposed for early diagnosis
and accurate staging and to guide decisions regarding patients with sepsis, severe sepsis …

Fast screening and primary diagnosis of COVID-19 by ATR–FT-IR

L Zhang, M Xiao, Y Wang, S Peng, Y Chen… - Analytical …, 2021 - ACS Publications
The outbreak of coronavirus disease 2019 (COVID-19) has led to substantial infections and
mortality around the world. Fast screening and diagnosis are thus crucial for quick isolation …

Utilidad de los biomarcadores de inflamación e infección en los servicios de urgencias

A Julián-Jiménez, FJ Candel-González… - … y Microbiología Clínica, 2014 - Elsevier
El 10% de las asistencias en los servicios de urgencias están relacionadas con procesos
infecciosos. Administrar el tratamiento antibiótico de manera precoz y la toma inmediata de …