Practical medical applications of quantitative MR relaxometry
HL Margaret Cheng, N Stikov… - Journal of Magnetic …, 2012 - Wiley Online Library
Conventional MR images are qualitative, and their signal intensity is dependent on several
complementary contrast mechanisms that are manipulated by the MR hardware and …
complementary contrast mechanisms that are manipulated by the MR hardware and …
Cartilage biomechanics: From the basic facts to the challenges of tissue engineering
Articular cartilage (AC) is the thin tissue that covers the long bone ends in the joints and that
ensures the transmission of forces between adjacent bones while allowing nearly …
ensures the transmission of forces between adjacent bones while allowing nearly …
Applications of vibrational spectroscopy for analysis of connective tissues
Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …
composition and structure of biological tissues. In this review, we discuss common …
Evaluation of principal component analysis image denoising on multi‐exponential MRI relaxometry
Purpose Multi‐exponential relaxometry is a powerful tool for characterizing tissue, but
generally requires high image signal‐to‐noise ratio (SNR). This work evaluates the use of …
generally requires high image signal‐to‐noise ratio (SNR). This work evaluates the use of …
Model-based MR parameter mapping with sparsity constraints: parameter estimation and performance bounds
Magnetic resonance parameter mapping (eg, T 1 mapping, T 2 mapping, T 2* mapping) is a
valuable tool for tissue characterization. However, its practical utility has been limited due to …
valuable tool for tissue characterization. However, its practical utility has been limited due to …
[HTML][HTML] Matrix degradation in osteoarthritis primes the superficial region of cartilage for mechanical damage
Osteoarthritis (OA) is a degenerative disease that affects 25% of the world's population over
fifty years of age. It is a chronic disease of the synovial joints, primarily the hip and knee. The …
fifty years of age. It is a chronic disease of the synovial joints, primarily the hip and knee. The …
Morphologic and quantitative magnetic resonance imaging of knee articular cartilage for the assessment of post‐traumatic osteoarthritis
Orthopedic trauma, such as anterior cruciate ligament (ACL) disruption, is a common source
of osteoarthritis in the knee. Magnetic resonance imaging (MRI) is a non‐invasive multi …
of osteoarthritis in the knee. Magnetic resonance imaging (MRI) is a non‐invasive multi …
Vibrational spectroscopy of articular cartilage
Articular cartilage is a connective tissue that is located at the ends of long bones. Type II
collagen, proteoglycans, water, and chondrocytes are the main constituents of articular …
collagen, proteoglycans, water, and chondrocytes are the main constituents of articular …
Machine learning prediction of collagen fiber orientation and proteoglycan content from multiparametric quantitative MRI in articular cartilage
SA Mirmojarabian, AW Kajabi… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Machine learning models trained with multiparametric quantitative MRIs
(qMRIs) have the potential to provide valuable information about the structural composition …
(qMRIs) have the potential to provide valuable information about the structural composition …
Monitoring cartilage tissue engineering using magnetic resonance spectroscopy, imaging, and elastography
A key technical challenge in cartilage tissue engineering is the development of a
noninvasive method for monitoring the composition, structure, and function of the tissue at …
noninvasive method for monitoring the composition, structure, and function of the tissue at …