The connectome of an insect brain
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
Dopamine dynamics and signaling in Drosophila: an overview of genes, drugs and behavioral paradigms
S Yamamoto, ES Seto - Experimental animals, 2014 - jstage.jst.go.jp
Changes in dopamine (DA) signaling have been implicated in a number of human
neurologic and psychiatric disorders. Similarly, defects in DA signaling in the fruit fly …
neurologic and psychiatric disorders. Similarly, defects in DA signaling in the fruit fly …
The roles of dopamine and related compounds in reward-seeking behavior across animal phyla
Motile animals actively seek out and gather resources they find rewarding, and this is an
extremely powerful organizer and motivator of animal behavior. Mammalian studies have …
extremely powerful organizer and motivator of animal behavior. Mammalian studies have …
The complete connectome of a learning and memory centre in an insect brain
Associating stimuli with positive or negative reinforcement is essential for survival, but a
complete wiring diagram of a higher-order circuit supporting associative memory has not …
complete wiring diagram of a higher-order circuit supporting associative memory has not …
A subset of dopamine neurons signals reward for odour memory in Drosophila
Animals approach stimuli that predict a pleasant outcome. After the paired presentation of an
odour and a reward, Drosophila melanogaster can develop a conditioned approach towards …
odour and a reward, Drosophila melanogaster can develop a conditioned approach towards …
Recurrent architecture for adaptive regulation of learning in the insect brain
Dopaminergic neurons (DANs) drive learning across the animal kingdom, but the upstream
circuits that regulate their activity and thereby learning remain poorly understood. We …
circuits that regulate their activity and thereby learning remain poorly understood. We …
[HTML][HTML] Dopamine is required for learning and forgetting in Drosophila
Psychological studies in humans and behavioral studies of model organisms suggest that
forgetting is a common and biologically regulated process, but the molecular, cellular, and …
forgetting is a common and biologically regulated process, but the molecular, cellular, and …
Drosophila mushroom bodies integrate hunger and satiety signals to control innate food-seeking behavior
The fruit fly can evaluate its energy state and decide whether to pursue food-related cues.
Here, we reveal that the mushroom body (MB) integrates hunger and satiety signals to …
Here, we reveal that the mushroom body (MB) integrates hunger and satiety signals to …
Specific dopaminergic neurons for the formation of labile aversive memory
A paired presentation of an odor and electric shock induces aversive odor memory in
Drosophila melanogaster [1, 2]. Electric shock reinforcement is mediated by dopaminergic …
Drosophila melanogaster [1, 2]. Electric shock reinforcement is mediated by dopaminergic …
Upregulated energy metabolism in the Drosophila mushroom body is the trigger for long-term memory
PY Placais, É de Tredern, L Scheunemann… - Nature …, 2017 - nature.com
Efficient energy use has constrained the evolution of nervous systems. However, it is
unresolved whether energy metabolism may resultantly regulate major brain functions. Our …
unresolved whether energy metabolism may resultantly regulate major brain functions. Our …