The visual system of zebrafish and its use to model human ocular diseases

G Gestri, BA Link, SCF Neuhauss - Developmental …, 2012 - Wiley Online Library
Free swimming zebrafish larvae depend mainly on their sense of vision to evade predation
and to catch prey. Hence, there is strong selective pressure on the fast maturation of visual …

Molecular basis of retinal remodeling in a zebrafish model of retinitis pigmentosa

A Santhanam, E Shihabeddin, H Wei, J Wu… - Cellular and Molecular …, 2023 - Springer
A hallmark of inherited retinal degenerative diseases such as retinitis pigmentosa (RP) is
progressive structural and functional remodeling of the remaining retinal cells as …

The male abnormal gene family 21 (Mab21) members regulate eye development

ZX Huang, JW Xiang, L Zhou, Q Nie… - Current molecular …, 2016 - ingentaconnect.com
The male abnormal gene family contains 3 members, named mab21l1, mab21l2 and
mab21l3. Since their first discovery in C. elegans, homologues of mab21l1 and mab21l2 …

[HTML][HTML] Spatial regulation of amacrine cell genesis by Semaphorin 3f

CL Hehr, R Halabi, S McFarlane - Developmental Biology, 2022 - Elsevier
Purpose The axonal projections of retinal ganglion cells (RGCs) of the eye are
topographically organized so that spatial information from visual images is preserved. This …

Morphological and physiological properties of enhanced green fluorescent protein (EGFP)‐expressing wide‐field amacrine cells in the C h AT‐EGFP mouse line

GC Knop, M Pottek, H Monyer… - European Journal of …, 2014 - Wiley Online Library
Mammalian retinas comprise a variety of interneurons, among which amacrine cells
represent the largest group, with more than 30 different cell types each exhibiting a rather …

mab21l2 transgenics reveal novel expression patterns of mab21l1 and mab21l2, and conserved promoter regulation without sequence conservation

ML Cederlund, V Vendrell, ME Morrissey… - Developmental …, 2011 - Wiley Online Library
Abstract mab21l1 and mab21l2 paralogs have widespread and dynamic expression
patterns during vertebrate development. Both genes are expressed in the developing eye …

Transcriptomic remodeling of the retina in a Zebrafish model of Retinitis Pigmentosa

A Santhanam, E Shihabeddin, H Wei, J Wu, J O'Brien - bioRxiv, 2022 - biorxiv.org
Inherited retinal degenerative diseases such as Retinitis Pigmentosa (RP) result in
progressive loss of photoreceptors until an individual is completely blind. A hallmark of these …

[HTML][HTML] The Usher gene cadherin 23 is expressed in the zebrafish brain and a subset of retinal amacrine cells

G Glover, KP Mueller, C Söllner, SCF Neuhauss… - Molecular …, 2012 - ncbi.nlm.nih.gov
Purpose To characterize the expression pattern of cadherin 23 (cdh23) in the zebrafish
visual system, and to determine whether zebrafish cdh23 mutants have retinal defects …

Developmental and adult characterization of secretagogin expressing amacrine cells in zebrafish retina

S Dudczig, PD Currie, PR Jusuf - Plos one, 2017 - journals.plos.org
Calcium binding proteins show stereotypical expression patterns within diverse neuron
types across the central nervous system. Here, we provide a characterization of …

Fluorescent tracer of dopamine enables selective labelling and interrogation of dopaminergic amacrine cells in the retina of living zebrafish

HJ Lin, ZY Hong, YK Li, I Liau - RSC advances, 2016 - pubs.rsc.org
The retinal dopaminergic amacrine cell plays multiple roles in vision; it optimizes the
encoding of visual stimuli, serves as an output of the circadian rhythm, and influences …