Proanthocyanidin alleviates testicular torsion/detorsion-induced ischemia/reperfusion injury in rats

F Kazak, G Akcakavak, I Alakus, H Alakus, O Kirgiz… - Tissue and Cell, 2024 - Elsevier
Testicular torsion is an urological emergency and can lead to ischemia damage and
testicular loss if not diagnosed in time. Proanthocyanidin is reported to have anti …

Protective effect of Smilax excelsa L. pretreatment via antioxidant, anti‐inflammatory effects, and activation of Nrf‐2/HO‐1 pathway in testicular torsion model

M Cellat, CT İşler, A Uyar, M Kuzu… - Journal of food …, 2022 - Wiley Online Library
The protective effects of the ethanol extract of Smilax excelsa L.(SE) leaves were
investigated on testicular tissue of rats with a torsion model in this study. The chemical …

Salidroside Exerts Beneficial Effect on Testicular Ischemia‐Reperfusion Injury in Rats

SM Wei, YM Huang, ZQ Qin - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
Testicular torsion‐detorsion results in testicular ischemia‐reperfusion injury, which is
associated with overgeneration of reactive oxygen species. Salidroside, a major bioactive …

Evaluating the effects of betaine on testicular ischemia/reperfusion injury induced by torsion/detorsion in the rat

M Sarlak, E Roumiani, A Kheradmand… - Andrologia, 2022 - Wiley Online Library
In this research, the effects of betaine on testicular ischemia–reperfusion were evaluated.
Forty rats were randomly divided into 4 groups of sham, torsion/detorsion (TD) …

Targeting soluble guanylate cyclase with riociguat has potency to alleviate testicular ischaemia reperfusion injury via regulating various cellular pathways

U Seker, DE Kavak, BC Guzel, SB Baygeldi… - Andrologia, 2022 - Wiley Online Library
Testicular ischaemia reperfusion (I/R) injury results with serious dysfunctions in testis. This
study aims to explore effects of soluble guanylate cyclase (sGC) stimulator Riociguat on …

Protective effects of rosmarinic acid on testicular torsion-detorsion in an animal model

A Raisi, F Davoodi, R Mohammadi - Iranian Journal of Veterinary …, 2022 - ivsajournals.com
Testicular torsion is a disorder that may cause infertility or subfertility in males. Rosmarinic
acid (RA) is a natural polyphenol with potent antioxidant effects that its protective effects in …

Evaluation of effects of Tempol on testicular ischemia/reperfusion injury

V Ganjiani, A Meimandi-Parizi, N Ahmadi… - The American Journal of …, 2024 - Elsevier
Aim Tempol, a synthetic antioxidant compound, has received significant attention for its
potential therapeutic applications in recent years, especially against ischemia/reperfusion …

Phoenixin-14 may ameliorate testicular damage caused by torsion-detorsion by reducing oxidative stress and inflammation in prepubertal rats

N Yilmaz, J Hudaykulıyeva, S Gul - Tissue and Cell, 2024 - Elsevier
The present study aimed to investigate the effects of Phoenixin-14 (PNX-14) on oxidative
damage, inflammatory response, histopathological variations, and serum testosterone levels …

HO-1 attenuates testicular ischaemia/reperfusion injury by activating the phosphorylated C-jun-miR-221/222-TOX pathway

B Xie, B Cheng, L He, Y Liu, N He - Heliyon, 2024 - cell.com
Abstract Aims Heme oxygenase (HO-1) affords protection against ischaemia/reperfusion
(I/R) injury; however, its effects on testicular I/R injury remain poorly explored. Herein, we …

Protective effects of Mito-TEMPO on ischemia-reperfusion injury in a mouse testicular torsion and detorsion model

Z Mostahsan, S Azizi, A Soleimanzadeh… - Veterinary Research …, 2024 - vrf.iranjournals.ir
Testicular ischemia-reperfusion (I/R) injury during testicular torsion is strongly influenced by
oxidative stress caused by excessive accumulation of unscavenged reactive oxygen …