Many animal models have been developed to study the causes and treatments of chronic
kidney disease (CKD) in humans, an insidious disease resulting from kidney injury and …

Transforming growth factor beta (TGF-β) has been recognized as an important mediator in
the genesis of chronic kidney diseases (CKD), which are characterized by the accumulation …

На рубеже XX и XXI веков мировое сообщество столкнулось с глобальной проблемой,
имеющей не только медицинское, но и огромное социально-экономическое значение …

Background: Proteinuria is a key biomarker in nephrology. It is central to diagnosis and risk
assessment and the primary target of many important therapies. Etiologies resulting in …

It has been reported that oxidative stress has a pivotal role in many disorders such as
chronic kidney diseases. Free radicals can directly attack cellular elements, trigger …

Stroke is a leading cause of mortality and morbidity, with long-term debilitating effects.
Accumulating evidence from experimental studies as well as observational studies in …

Background The incidence of human chronic kidney failure with associated cardiovascular
disease is increasing. Kidney damage can be induced in rats by chronic dietary adenine …

This study aims to determine the potential protective effects of ferulic acid against cisplatin-
induced nephrotoxicity and to compare its effect with curcumin, a well-known protective …

The use of tenofovir disoproxil fumarate has been associated with side effects on renal
function and bone mineral density, but whether this toxicity is of clinical relevance in the …

Objectives Chronic kidney disease (CKD), a progressive and irreversible pathological
syndrome, is the major cause of renal failure. Renal fibrosis is the principal process …