Imprinted small nucleolar RNAs: Missing link in development and disease?

K Gawade, KD Raczynska - Wiley Interdisciplinary Reviews …, 2024 - Wiley Online Library
Abstract The 14q32. 2 (DLK1‐DIO3) and 15q11‐q13 (SNURF‐SNRPN) imprinted gene loci
harbor the largest known small nucleolar RNA clusters expressed from the respective …

Potential molecular mechanisms and clinical implications of piRNAs in preeclampsia: a review

Y Ma, B Hou, J Zong, S Liu - Reproductive Biology and Endocrinology, 2024 - Springer
Preeclampsia is a multisystem progressive condition and is one of the most serious
complications of pregnancy. Owing to its unclear pathogenesis, there are no precise and …

[HTML][HTML] The expression profiles of piRNAs and their interacting Piwi proteins in cellular model of renal development: Focus on Piwil1 in mitosis

M Kazimierczyk, A Fedoruk-Wyszomirska… - European Journal of …, 2024 - Elsevier
Piwi proteins and Piwi interacting RNAs, piRNAs, presented in germline cells play a role in
transposon silencing during germline development. In contrast, the role of somatic Piwi …

piOxi database: a web resource of germline and somatic tissue piRNAs identified by chemical oxidation

K Wang, BPU Perera, RK Morgan, K Sala-Hamrick… - Database, 2024 - academic.oup.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that are highly
expressed and extensively studied from the germline. piRNAs associate with PIWI proteins …

Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure

BPU Perera, K Wang, D Wang, K Chen, A Dewald… - Epigenetics, 2024 - Taylor & Francis
Lead (Pb) is a neurotoxicant with early life exposure linked to long-term health effects. Piwi-
interacting RNAs (piRNAs) are small non-coding RNAs that associate with PIWIL proteins to …

Small non-coding RNAs in the human placenta: regulatory roles and clinical utility

N Telkar, GL Stewart, ME Pewarchuk, DE Cohn… - Frontiers in …, 2022 - frontiersin.org
The placenta is a vital organ formed during pregnancy, and being the interface between the
mother and fetus, it is paramount that placental functioning is strictly controlled. Gene …

Synergistic Immunoregulation: harnessing CircRNAs and PiRNAs to Amplify PD-1/PD-L1 Inhibition Therapy

R Han, X Rao, H Zhou, L Lu - International Journal of …, 2024 - Taylor & Francis
The utilization of PD-1/PD-L1 inhibitors marks a significant advancement in cancer therapy.
However, the efficacy of monotherapy is still disappointing in a substantial subset of patients …

Construction and Current Status of the International Authoritative PIWI-Interacting RNA Database Platform

S He, J Wang, P Zhang - China's e-Science Blue Book 2023, 2024 - Springer
Abstract piRNA (PIWI-interacting RNA) is a kind of small noncoding RNA mainly expressed
in germ cells and bound to PIWI proteins. It plays an important role in germ cells and gene …