In this review, we describe a detailed investigation about the structural variations and
relative activity of 1, 8-naphthalimide based intercalators and anticancer agents. The 1, 8 …

Antibody–drug conjugates (ADCs) comprise antibodies, cytotoxic payloads, and linkers,
which can integrate the advantages of antibodies and small molecule drugs to achieve …

Lysosome-targeting self-assembling prodrugs had emerged as an attractive approach to
overcome the acquisition of resistance to chemotherapeutics by inhibiting lysosomal …

Introduction: Naphthalimides are important aromatic heterocycles with immense
pharmacological significance as they serve as core scaffold for many antitumor, anti …

Naphthalimide compounds are an important type of nitrogen-containing aromatic
heterocycles with cyclic double imides and the naphthalene framework. This π-deficient …

Traditional drug delivery systems suffer from low drug-loading and relatively weak
therapeutic efficacy, therefore, development of new drug delivery systems with high …

Four series of new 3-nitro naphthalimides derivatives, 4 (4a‒4f), 5 (5a‒5i), 6 (6a‒6e) and 7
(7a‒7j), were designed and synthesized as antitumor agents. Methyl thiazolyl tetrazolium …

In this study we extracted bioactive ingredients from fruiting bodies of Laetiporus sulphureus
with different solvents and tested the antimicrobial and antitumor activities. The predominant …

A series of 4β-alkylamidochalcone and 4β-cinnamido linked podophyllotoxin congeners
have been synthesized. All the twenty nine compounds were evaluated for anticancer …

The Accum™ technology was initially designed to enhance the bioaccumulation of a given
molecule in target cells. It does so by triggering endosomal membrane damages allowing …