The complement system is a key innate immune defence against infection and an important
driver of inflammation; however, these very properties can also cause harm. Inappropriate or …

The complement system is a set of immune proteins involved in first-line defense against
pathogens and removal of waste materials. Recent evidence has implicated the complement …

Identifying biomarkers that can be used as diagnostics or predictors of treatment response
(theranostics) in people with schizophrenia (Sz) will be an important step towards being able …

Recent research efforts have progressively shifted towards preventative psychiatry and
prognostic identification of individuals before disease onset. We describe the development …

Importance Biomarkers that are predictive of outcomes in individuals at risk of psychosis
would facilitate individualized prognosis and stratification strategies. Objective To …

Current evidence indicates that certain immune molecules such as components of the
complement system are directly involved in neurobiological processes related to brain …

Early identification and treatment significantly improve clinical outcomes of psychotic
disorders. Recent studies identified protein components of the complement and coagulation …

Recent improvements in high-throughput proteomic approaches are likely to constitute an
essential advance in biomarker discovery, holding promise for improved personalized care …

Immunological/inflammatory factors are implicated in the development of psychosis.
Complement is a key driver of inflammation; however, it remains unknown which factor is …

Many studies have identified changes in gene expression in brains of schizophrenia
patients and their altered molecular processes, but the findings in different datasets were …