Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits

KJ Ressler, S Berretta, VY Bolshakov… - Nature Reviews …, 2022 - nature.com
Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …

Emotion processing dysfunction in Alzheimer's disease: an overview of behavioral findings, systems neural correlates, and underlying neural biology

S Chaudhary, S Zhornitsky, HH Chao… - American Journal of …, 2022 - journals.sagepub.com
We described behavioral studies to highlight emotional processing deficits in Alzheimer's
disease (AD). The findings suggest prominent deficit in recognizing negative emotions …

Analysis of Field Dependent and Field Independent Cognitive Styles in Solving Science Problems in Elementary Schools

F Hardiansyah, A Armadi, MM AR… - Jurnal Penelitian …, 2024 - jppipa.unram.ac.id
This research aims to determine the results of the Science Problem Solving Test, describing
students' Field Dependent and Field Independent cognitive styles in solving science …

Regulatory functions of FKBP5 intronic regions associated with psychiatric disorders

MS Mendonça, PM Mangiavacchi, ÁFL Rios - Journal of Psychiatric …, 2021 - Elsevier
The FKBP5 gene codifies a co-chaperone protein associated with the modulation of
glucocorticoid receptor interaction involved in the adaptive stress response. The FKBP5 …

Structure and function of the TPR‐domain immunophilins FKBP51 and FKBP52 in normal physiology and disease

OB Soto, CS Ramirez, R Koyani… - Journal of Cellular …, 2023 - Wiley Online Library
Coordinated cochaperone interactions with Hsp90 and associated client proteins are crucial
for a multitude of signaling pathways in normal physiology, as well as in disease settings …

Mechanistic study of the formation of arbutin polymorphs and solvates

M Taiwaikuli, T Wang, K Chen, Y Feng, J Xing… - …, 2023 - pubs.rsc.org
In this study, the complicated solvation behaviors of arbutin were studied from both
experiment investigations and theoretical calculations. Six solid forms of arbutin, namely the …

Prolonged early exposure to a high-fat diet augments the adverse effects on Neurobehavior and hippocampal neuroplasticity: involvement of microglial insulin …

X Yao, J Zhao, Y Yuan, C Wang, Z Yu, Z Huang… - The American Journal of …, 2023 - Elsevier
High-fat diet (HFD) consumption may contribute to the high prevalence of cognitive–
emotional issues in modern society. Mice fed a HFD for a prolonged period develop more …

FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin

B Qiu, Z Zhong, S Righter, Y Xu, J Wang… - Cellular and Molecular …, 2022 - Springer
Abstract FK506-binding protein 51 (encoded by Fkpb51, also known as Fkbp5) has been
associated with stress-related mental illness. To investigate its function, we studied the …

Genetically engineered mouse models of FK506‐binding protein 5

NT Gebru, SE Hill, LJ Blair - Journal of Cellular Biochemistry, 2023 - Wiley Online Library
Abstract FK506 binding protein 51 (FKBP51) is a molecular chaperone that influences stress
response. In addition to having an integral role in the regulation of steroid hormone …

Treatment efficacy of tDCS and predictors of treatment response in patients with post-traumatic stress disorder

J Han, K Choi, C Yang, HS Kim, SS Park… - Journal of Affective …, 2022 - Elsevier
Background Although transcranial direct stimulation (tDCS) has been proposed as an
alternative treatment option for various psychiatric disorders, there is inconsistent …