Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Helicobacter pylori infection: from standard to alternative treatment strategies

C Sousa, R Ferreira, NF Azevedo… - Critical reviews in …, 2022 - Taylor & Francis
Helicobacter pylori is the major component of the gastric microbiome of infected individuals
and one of the aetiological factors of chronic gastritis, peptic ulcer disease and gastric …

Designing, characterization, and immune stimulation of a novel multi-epitopic peptide-based potential vaccine candidate against monkeypox virus through screening …

M Bhattacharya, S Chatterjee, S Nag, K Dhama… - Travel Medicine and …, 2022 - Elsevier
Background The current monkeypox virus (MPXV) spread in the non-epidemic regions
raises global concern. Presently, the smallpox vaccine is used against monkeypox with …

Molecular docking and molecular dynamics studies reveal secretory proteins as novel targets of temozolomide in glioblastoma multiforme

Sumera, F Anwer, M Waseem, A Fatima, N Malik, A Ali… - Molecules, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is a tumor of glial origin and is the most malignant,
aggressive and prevalent type, with the highest mortality rate in adult brain cancer. Surgical …

Plant-Based Bioactive Phthalates Derived from Hibiscus rosa-sinensis: As In Vitro and In Silico Enzyme Inhibition

F Yasmin, ZH Nazli, N Shafiq, M Aslam… - ACS …, 2023 - ACS Publications
Hibiscus rosa-sinensis is an attractive, ever-blossoming, and effortlessly available plant
around the globe. The fabulous flowers of H. rosa-sinensis enjoy a significant status in folk …

In-Silico Vaccine Design Based on a Novel Vaccine Candidate Against Infections Caused by Acinetobacter baumannii

K Khalid, S Irum, SR Ullah, S Andleeb - International journal of peptide …, 2022 - Springer
Acinetobacter baumannii is notorious for causing serious infections of the skin, lungs, soft
tissues, bloodstream, and urinary tract. Despite the overwhelming information available so …

[HTML][HTML] A next-generation vaccine candidate using alternative epitopes to protect against Wuhan and all significant mutant variants of SARS-CoV-2: an …

M Bhattacharya, AR Sharma, P Ghosh, SS Lee… - Aging and …, 2021 - ncbi.nlm.nih.gov
Newly emerging significant SARS-CoV-2 variants such as B. 1.1. 7, B. 1.351, and B. 1.1. 28
are the variant of concern (VOC) for the human race. These variants are getting challenging …

[HTML][HTML] MM-GBSA and QM/MM simulation-based in silico approaches for the inhibition of Acinetobacter baumannii class D OXA-24 β-lactamase using antimicrobial …

M Mandal, S Mandal - Chemical Physics Impact, 2024 - Elsevier
The antimicrobial peptides (AMPs) have been regarded as the next generation antibiotics.
This study aimed to explore the AMP inhibitors of β-lactamase enzyme employing …

Exploring antidiabetic potential of a polyherbal formulation Madhurakshak Activ: An in vitro and in silico study

S Paul, M Majumdar - Fitoterapia, 2023 - Elsevier
Madhurakshak Activ (MA), a commercial polyherbal antidiabetic preparation is known to
manage diabetes mellitus (DM) by reducing blood glucose levels. However, lacks …

Assessing the efficacy of cinnamon compounds against H. pylori through molecular docking, MD Simulations and ADMET analyses

MF Sarwar, A Zahra, MF Awan, S Ali, M Shafiq… - Plos one, 2024 - journals.plos.org
Antibiotics are the drugs that are used for the management of microbial diseases. However,
these conventional synthetic drugs can harmfully affect the human health. Since …