The emergence and influence of internal states

SW Flavell, N Gogolla, M Lovett-Barron, M Zelikowsky - Neuron, 2022 - cell.com
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

Neurobehavioral meaning of pupil size

N Grujic, R Polania, D Burdakov - Neuron, 2024 - cell.com
Pupil size is a widely used metric of brain state. It is one of the few signals originating from
the brain that can be readily monitored with low-cost devices in basic science, clinical, and …

Stimulus-dependent representational drift in primary visual cortex

TD Marks, MJ Goard - Nature communications, 2021 - nature.com
To produce consistent sensory perception, neurons must maintain stable representations of
sensory input. However, neurons in many regions exhibit progressive drift across days …

State-dependent pupil dilation rapidly shifts visual feature selectivity

K Franke, KF Willeke, K Ponder, M Galdamez, N Zhou… - Nature, 2022 - nature.com
To increase computational flexibility, the processing of sensory inputs changes with
behavioural context. In the visual system, active behavioural states characterized by motor …

Visual thalamocortical mechanisms of waking state-dependent activity and alpha oscillations

DB Nestvogel, DA McCormick - Neuron, 2022 - cell.com
The brain exhibits distinct patterns of recurrent activity closely related to behavioral state.
The neural mechanisms that underlie state-dependent activity in the awake animal are …

Flexible neural population dynamics govern the speed and stability of sensory encoding in mouse visual cortex

EAB Horrocks, FR Rodrigues, AB Saleem - Nature Communications, 2024 - nature.com
Time courses of neural responses underlie real-time sensory processing and perception.
How these temporal dynamics change may be fundamental to how sensory systems adapt …

Cortical reactivations predict future sensory responses

ND Nguyen, A Lutas, O Amsalem, J Fernando… - Nature, 2024 - nature.com
Many theories of offline memory consolidation posit that the pattern of neurons activated
during a salient sensory experience will be faithfully reactivated, thereby stabilizing the …

[HTML][HTML] Psilocybin induces spatially constrained alterations in thalamic functional organizaton and connectivity

A Gaddis, DE Lidstone, MB Nebel, RR Griffiths… - Neuroimage, 2022 - Elsevier
Background Classic psychedelics, such as psilocybin and LSD, and other serotonin 2A
receptor (5-HT 2AR) agonists evoke acute alterations in perception and cognition. Altered …

Brainstem serotonin neurons selectively gate retinal information flow to thalamus

JDS Reggiani, Q Jiang, M Barbini, A Lutas, L Liang… - Neuron, 2023 - cell.com
Retinal ganglion cell (RGC) types relay parallel streams of visual feature information. We
hypothesized that neuromodulators might efficiently control which visual information streams …

Eavesdropping wires: Recording activity in axons using genetically encoded calcium indicators

GJ Broussard, L Petreanu - Journal of neuroscience methods, 2021 - Elsevier
Neurons broadcast electrical signals to distal brain regions through extensive axonal arbors.
Genetically encoded calcium sensors permit the direct observation of action potential activity …