Assortative mating biases marker-based heritability estimators

R Border, S O'Rourke, T de Candia… - Nature …, 2022 - nature.com
Many traits are subject to assortative mating, with recent molecular genetic findings
confirming longstanding theoretical predictions that assortative mating induces long range …

SLEMM: million-scale genomic predictions with window-based SNP weighting

J Cheng, C Maltecca, PM VanRaden… - …, 2023 - academic.oup.com
Motivation The amount of genomic data is increasing exponentially. Using many genotyped
and phenotyped individuals for genomic prediction is appealing yet challenging. Results We …

Optimization of Computations for Structural Equation Modeling with Applications in Bionformatics

GA Meshcheryakov, VA Zuev, AA Igolkina… - Biophysics, 2022 - Springer
Structural equation modeling (SEM) is a technique for analysis of linear relations
represented as the causal and correlational relationships between observed and latent …

Учредители: ФИЦ" Пущинский научный центр биологических исследований РАН", Российская академия наук, Отделение биохимии, биофизики и химии …

ГА Мещеряков, ВА Зуев, АА Иголкина, МГ Самсонова - Биофизика, 2022 - elibrary.ru
Структурное моделирование уравнениями-это метод для анализа линейных
взаимодействий между наблюдаемыми и латентными переменными …

Hybrid of Restricted and Penalized Maximum Likelihood Method for Efficient Genome-wide Association Study

W Ren, Z Liang, S He, J Xiao - Genes, 2020 - mdpi.com
In genome-wide association studies, linear mixed models (LMMs) have been widely used to
explore the molecular mechanism of complex traits. However, typical association …

Topics in the Quantitative Analysis of Complex Trait Genetic Architectures

R Border - 2019 - search.proquest.com
The unprecedented availability of whole-genome data in recent years has allowed
researchers to ask new questions regarding the genetic underpinnings of human traits while …