Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …

Alzheimer's disease is the main cause of dementia in the elderly and begins with a subtle
decline in episodic memory followed by a more general decline in overall cognitive abilities …

In humans, temporal lobe epilepsy (TLE) is often associated with Ammon's horn sclerosis
(AHS) characterized by hippocampal cell death, gliosis and granule cell dispersion (GCD) in …

The inwardly rectifying K+ channel subtype Kir5. 1 is only functional as a heteromeric
channel with Kir4. 1. In the CNS, Kir4. 1 is localised to astrocytes and is the molecular basis …

Electrical stimulation is emerging as a viable alternative for patients with epilepsy whose
seizures are not alleviated by drugs or surgery. Its attractions are temporal and spatial …

Melatonin is a pleiotropic biofactor and an effective antioxidant and free radical scavenger
and, as such, can be protective in oxidative stress‐related brain conditions including …

Background and Purpose Inward rectifier potassium (KIR) channels are key effectors of
vasodilatation in neurovascular coupling (NVC). KIR channels expressed in cerebral …

Inward rectifier currents based on KIR2. x subunits are regarded as essential components
for establishing a stable and negative resting membrane potential in many excitable cell …

Astrocytes express potassium and water channels to support dynamic regulation of
potassium homeostasis. Potassium kinetics can be modulated by aquaporin-4 (AQP4), the …

Absence seizures are characterized by cortical spike-wave discharges (SWDs) on
electroencephalography, often accompanied by a shift in the firing pattern of thalamocortical …