Biofilm dispersion

KP Rumbaugh, K Sauer - Nature Reviews Microbiology, 2020 - nature.com
The formation of microbial biofilms enables single planktonic cells to assume a multicellular
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …

Challenges of intervention, treatment, and antibiotic resistance of biofilm-forming microorganisms

G Gebreyohannes, A Nyerere, C Bii, DB Sbhatu - Heliyon, 2019 - cell.com
Background Biofilms are multicellular communities of microorganisms held together by a self-
produced extracellular matrix. The ability of microbes to form biofilm is a universal …

Fatty acids as antibiofilm and antivirulence agents

P Kumar, JH Lee, H Beyenal, J Lee - Trends in microbiology, 2020 - cell.com
Fatty acids (FAs) have emerged as a potential alternative to conventional antibiotics. Since
many microbes respond differently to a variety of natural and synthetic FAs, substantial …

Approaches to dispersing medical biofilms

D Fleming, KP Rumbaugh - Microorganisms, 2017 - mdpi.com
Biofilm-associated infections pose a complex problem to the medical community, in that
residence within the protection of a biofilm affords pathogens greatly increased tolerances to …

Targeting biofilms therapy: current research strategies and development hurdles

Y Jiang, M Geng, L Bai - Microorganisms, 2020 - mdpi.com
Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …

Biofilms in food processing environments: challenges and opportunities

A Alvarez-Ordóñez, LM Coughlan… - Annual Review of …, 2019 - annualreviews.org
This review examines the impact of microbial communities colonizing food processing
environments in the form of biofilms on food safety and food quality. The focus is both on …

Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO)

Y Wo, EJ Brisbois, RH Bartlett, ME Meyerhoff - Biomaterials science, 2016 - pubs.rsc.org
Biomedical devices are essential for patient diagnosis and treatment; however, when blood
comes in contact with foreign surfaces or homeostasis is disrupted, complications including …

Anti-biofilm activity as a health issue

S Miquel, R Lagrafeuille, B Souweine… - Frontiers in …, 2016 - frontiersin.org
The formation and persistence of surface-attached microbial communities, known as
biofilms, are responsible for 75% of human microbial infections (National Institutes of …

The DSF family of cell–cell signals: an expanding class of bacterial virulence regulators

RP Ryan, S An, JH Allan, Y McCarthy, JM Dow - PLoS pathogens, 2015 - journals.plos.org
Many pathogenic bacteria use cell–cell signaling systems involving the synthesis and
perception of diffusible signal molecules to control virulence as a response to cell density or …

Alternative antimicrobials: the properties of fatty acids and monoglycerides

CP Churchward, RG Alany… - Critical reviews in …, 2018 - Taylor & Francis
With the rising antibiotic resistance of many bacterial species, alternative treatments are
necessary to combat infectious diseases. The World Health Organization and the US …