Antiviral drug delivery system for enhanced bioactivity, better metabolism and pharmacokinetic characteristics
R Chen, T Wang, J Song, D Pu, D He, J Li… - International journal …, 2021 - Taylor & Francis
Antiviral drugs (AvDs) are the primary resource in the global battle against viruses, including
the recent fight against corona virus disease 2019 (COVID-19). Most AvDs require multiple …
the recent fight against corona virus disease 2019 (COVID-19). Most AvDs require multiple …
TPGS surface modified bilosomes as boosting cytotoxic oral delivery systems of curcumin against doxorubicin resistant MCF-7 breast cancer cells
The goal of this work was to design nude bilosomes (Bil) and D-alpha-tocopheryl
polyethylene glycol succinate (TPGS) surface coated bilosomes as an oral delivery platform …
polyethylene glycol succinate (TPGS) surface coated bilosomes as an oral delivery platform …
'Poly phenolic phytoceutical loaded nano-bilosomes for enhanced caco-2 cell permeability and SARS-CoV 2 antiviral activity': in-vitro and insilico studies
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) predisposed to the
emergence of worldwide catastrophe that impels the evolution of safe and effective …
emergence of worldwide catastrophe that impels the evolution of safe and effective …
Ultra-deformable free fatty acid based nano-carriers for topical delivery of Luteolin: A potential paradigm for management of Methicillin-Resistant Staphylococcus …
The incidences of antimicrobial resistance in particular, Methicillin-Resistant Staphylococcus
aureus (MRSA) have increased during the last two decades. However, conventional dosage …
aureus (MRSA) have increased during the last two decades. However, conventional dosage …
Design and synthesis of new trimethoxylphenyl-linked combretastatin analogues loaded on diamond nanoparticles as a panel for ameliorated solubility and …
I Zaki, AMY Moustafa, BY Beshay… - Journal of enzyme …, 2022 - Taylor & Francis
A new series of vinyl amide-, imidazolone-, and triazinone-linked combretastatin A-4
analogues have been designed and synthesised. These compounds have been evaluated …
analogues have been designed and synthesised. These compounds have been evaluated …
Design, green synthesis and tailoring of vitamin E TPGS augmented niosomal nano-carrier of pyrazolopyrimidines as potential anti-liver and breast cancer agents with …
VEGF plays a crucial role in cancer development, angiogenesis and progression, principally
liver and breast cancer. It is vital to uncover novel chemical candidates of VEGFR inhibitors …
liver and breast cancer. It is vital to uncover novel chemical candidates of VEGFR inhibitors …
Employment of PEGylated ultra-deformable transferosomes for transdermal delivery of tapentadol with boosted bioavailability and analgesic activity in post-surgical …
P Deng, RE Masoud, WM Alamoudi… - International journal of …, 2022 - Elsevier
The utilization of the proper and safe analgesics was considered a major concern in pain
alleviation especially that associated with surgical procedures. Novel analgesics as …
alleviation especially that associated with surgical procedures. Novel analgesics as …
Statistical optimization of bile salt deployed nanovesicles as a potential platform for oral delivery of piperine: accentuated antiviral and anti-inflammatory activity in …
The objective of this paper is to confine piperine, a poor oral bioavailable herbal drug into
bile salt based nano vesicles for improving its aqueous solubility, hence, its therapeutic …
bile salt based nano vesicles for improving its aqueous solubility, hence, its therapeutic …
Stabilized oral nanostructured lipid carriers of Adefovir Dipivoxil as a potential liver targeting: Estimation of liver function panel and uptake following intravenous …
Purpose Adefovir dipivoxil (AD), a nucleoside reverse transcriptase inhibitor is effective
against Hepatitis B virus. Its poor oral bioavailability leads to frequent administration causing …
against Hepatitis B virus. Its poor oral bioavailability leads to frequent administration causing …
Novel therapeutic approaches for the management of hepatitis infections
A Damodaran, SM Zachariah, SC Nair - Therapeutic Delivery, 2024 - Taylor & Francis
Hepatitis B virus (HBV) & hepatitis C virus (HCV) infection is a substantial reason for
morbidity and mortality around the world. Chronic hepatitis B (CHB) infection is connected …
morbidity and mortality around the world. Chronic hepatitis B (CHB) infection is connected …