Gout is a common inflammatory arthritis caused by persistently elevated uric acid levels.
With the improvement of people's living standards, the consumption of processed food and …

Excessive inflammatory reactions caused by uric acid deposition are the key factor leading
to gout. However, clinical medications cannot simultaneously remove uric acid and eliminate …

Gout represents an autoinflammatory disorder instigated by monosodium urate crystals. Its
primary manifestation involves the recruitment of diverse immune cell populations, including …

Background: Gout is a common arthritis, due to deposition of monosodium urate (MSU)
crystals which results in IL-1β secretion by tissue-resident macrophages. Xanthine oxidase …

There is an urgent need for alternative therapies targeting human dendritic cells (DCs) that
could reverse inflammatory syndromes in many autoimmune and inflammatory diseases and …

Background Acute gouty arthritis is inflammatory joint arthritis. Gouty arthritis (GA) involves
multiple pathological processes. Deposition of joints by monosodium urate (MSU) crystals …

Background: Gouty arthritis causes severe pain and inflammation. Alginate oligosaccharides
(AOSs) are natural products derived from alginate and have anti-inflammatory properties …

Hyperuricemia contributes significantly to gout arthritis pathogenesis, which promotes urate
crystal deposition in the joints and activates joint-resident macrophages and circulating …

Gout is an autoimmune disease characterized by acute or chronic inflammation and damage
to bone joints induced due to the precipitation of monosodium urate (MSU) crystals. In recent …

Polygallic acid (PGAL) has been used in vitro to protect synoviocytes from monosodium
urate (MSU) crystals due to its anti-inflammatory properties. However, MSU crystals can also …