Viroporins are small, hydrophobic proteins that are encoded by a wide range of clinically
relevant animal viruses. When these proteins oligomerize in host cell membranes, they form …

During the past 6 years, focused virus hunting has led to the discovery of nine new human
polyomaviruses, including Merkel cell polyomavirus, which has been linked to Merkel cell …

Papillomaviruses (PVs) are established agents of human and animal cancers. They infect
cutaneous and mucous epithelia. High Risk (HR) Human PVs (HPVs) are consistently …

The family Polyomaviridae encompasses non-enveloped viruses with a circular dsDNA
genome that is typically approximately 5000 bp in length. Originally isolated from mammals …

Herpesvirus capsids are assembled in the nucleus of infected cells whereas final maturation
occurs in the cytosol. To access the final maturation compartment, intranuclear capsids have …

The name of the family Polyomaviridae, derives from the early observation that cells infected
with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised …

Viroporins possess important potential as antiviral targets due to their critical roles during
virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine …

The channel-forming activity of a family of small, hydrophobic integral membrane proteins
termed 'viroporins' is essential to the life cycles of an increasingly diverse range of RNA and …

Polyomavirus BK (BKPyV) infects most people subclinically during childhood and
establishes a lifelong infection in the renourinary tract. In most immunocompetent …

Viroporins are virally encoded transmembrane proteins that are essential for viral
pathogenicity and can participate in various stages of the viral life cycle, thereby promoting …