Highlights•Cytochrome P450 enzymes catalyse oxygen insertion into a wide range of
substrates.•Mutagenesis of P450s frequently allows novel substrate recognition.•P450s …

Direct C–H bond functionalization catalyzed by non-precious transition metals is an
attractive strategy in synthetic chemistry. Compared with the precious metals rhodium …

The EUROFUNG network is a virtual centre of multidisciplinary expertise in the field of fungal
biotechnology. The first academic-industry Think Tank was hosted by EUROFUNG to …

Chiral amines are valuable constituents of many important pharmaceutical compounds and
their intermediates. It is estimated that∼ 40%–45% of small molecule pharmaceuticals …

For the planning of an organic synthesis route, the disconnection approach guided by
retrosynthetic analysis of possible intermediates and the chemical reactions involved, back …

Recent advances in metabolic engineering have demonstrated the potential to exploit
biological chemistry for the synthesis of complex molecules. Much of the progress to date …

Plants possess myriads of secondary metabolites with a broad spectrum of health-promoting
benefits. To date, plant extraction is still the primary route to produce high-value natural …

In a fundamental process throughout nature, reduced iron unleashes the oxidative power of
hydrogen peroxide into reactive intermediates. However, notwithstanding much work, the …

Covering: up to January 2017 Cytochrome P450 enzymes (P450s) are some of the most
exquisite and versatile biocatalysts found in nature. In addition to their well-known roles in …

Oil spillage is one of the most common pollutants which brings greater economic loss and
damage to the environment. The intensity and amount of the damage may vary depending …