Hyperpolarized 3 He gas allows the air spaces of the lungs to be imaged via MRI. Imaging of restricted diffusion is addressed here, which allows the microstructure of the lung to be …
Purpose To compare in vivo lung morphometry parameters derived from theoretical gas diffusion models, the cylinder model and stretched exponential model, in a range of acinar …
M Zhang, H Li, H Li, X Zhao, Q Zhou… - Magnetic …, 2020 - Wiley Online Library
Purpose To demonstrate the feasibility of 129Xe MR in evaluating the pulmonary physiological changes caused by PM2. 5 in animal models. Methods Six rats were treated …
Purpose Multi‐b diffusion‐weighted hyperpolarized inhaled‐gas MRI provides imaging biomarkers of terminal airspace enlargement including ADC and mean linear intercept (Lm) …
AV Ouriadov, MS Fox, AA Lindenmaier, E Stirrat… - … Resonance Materials in …, 2021 - Springer
Abstract Objective Diffusion-weighted, hyperpolarized 129 Xe MRI is useful for the characterization of microstructural changes in the lung. A stretched exponential model was …
Multi-b diffusion-weighted hyperpolarized gas MRI measures pulmonary airspace enlargement using apparent diffusion coefficients (ADC) and mean linear intercepts (L m) …
R Sembhi, T Ranota, M Fox, M Couch, T Li, I Ball… - Diagnostics, 2023 - mdpi.com
Dynamic inhaled gas (3He/129Xe/19F) MRI permits the acquisition of regional fractional- ventilation which is useful for detecting gas-trapping in lung-diseases such as lung fibrosis …
There are serious clinical gaps in our understanding of chronic lung disease that require novel, sensitive, and noninvasive in vivo measurements of the lung parenchyma to measure …