[HTML][HTML] Role of phytochemicals in cancer chemoprevention: Insights

BP George, R Chandran, H Abrahamse - Antioxidants, 2021 - mdpi.com
Cancer is a condition where the body cells multiply in an uncontrollable manner.
Chemoprevention of cancer is a broad term that describes the involvement of external …

Small molecules regulating reactive oxygen species homeostasis for cancer therapy

J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …

Retinoic acid and its derivatives in skin

Ł Szymański, R Skopek, M Palusińska, T Schenk… - Cells, 2020 - mdpi.com
The retinoids are a group of compounds including vitamin A and its active metabolite all-
trans-retinoic acid (ATRA). Retinoids regulate a variety of physiological functions in multiple …

Anoikis resistance––protagonists of breast cancer cells survive and metastasize after ECM detachment

Y Dai, X Zhang, Y Ou, L Zou, D Zhang, Q Yang… - Cell Communication and …, 2023 - Springer
Breast cancer exhibits the highest global incidence among all tumor types. Regardless of
the type of breast cancer, metastasis is a crucial cause of poor prognosis. Anoikis, a form of …

Targeting breast cancer stem cells through retinoids: a new hope for treatment

N Jan, S Sofi, H Qayoom, BU Haq, A Shabir… - Critical Reviews in …, 2023 - Elsevier
Breast cancer is a complex and diverse disease accounting for nearly 30% of all cancers
diagnosed in females. But unfortunately, patients develop resistance to the existing …

Tazarotene released from aligned electrospun membrane facilitates cutaneous wound healing by promoting angiogenesis

Z Zhu, Y Liu, Y Xue, X Cheng, W Zhao… - … applied materials & …, 2019 - ACS Publications
Wound treatment is a long-lasting clinical issue. Poor angiogenesis leading to delayed
wound closure causes huge challenges for healing. Functional electrospun membranes …

Nutritive vitamins as epidrugs

SM Nur, S Rath, V Ahmad, A Ahmad… - Critical reviews in …, 2021 - Taylor & Francis
Epigenetic modifications play an important role in disease pathogenesis and therefore are a
focus of intense investigation. Epigenetic changes include DNA, RNA, and histone …

Integrated microbiome, metabolome, and proteome analysis identifies a novel interplay among commensal bacteria, metabolites and candidate targets in non‐small …

X Qian, HY Zhang, QL Li, GJ Ma, Z Chen… - Clinical and …, 2022 - Wiley Online Library
Background Accumulation of evidence suggests that the gut microbiome, its specific
metabolites, and differentially expressed proteins (DEPs) are related to non‐small cell lung …

Phytotherapy and nutritional supplements on breast cancer

CM Lopes, A Dourado, R Oliveira - BioMed research …, 2017 - Wiley Online Library
Breast cancer is the most frequent type of nonskin malignancy among women worldwide. In
general, conventional cancer treatment options (ie, surgery, radiotherapy, chemotherapy …

Valproate and retinoic acid in combination with decitabine in elderly nonfit patients with acute myeloid leukemia: results of a multicenter, randomized, 2× 2, phase II …

M Lübbert, O Grishina, C Schmoor… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE DNA-hypomethylating agents are studied in combination with other epigenetic
drugs, such as histone deacetylase inhibitors or differentiation inducers (eg, retinoids), in …