Ultra-high field diffusion MRI reveals early axonal pathology in spinal cord of ALS mice

RG Gatto, MY Amin, D Deyoung, M Hey… - Translational …, 2018 - Springer
Background Amyotrophic lateral sclerosis (ALS) is a disease characterized by a progressive
degeneration of motor neurons leading to paralysis. Our previous MRI diffusion tensor …

Pore size estimation in axon‐mimicking microfibers with diffusion‐relaxation MRI

EJ Canales‐Rodríguez, M Pizzolato… - Magnetic …, 2024 - Wiley Online Library
Purpose This study aims to evaluate two distinct approaches for fiber radius estimation using
diffusion‐relaxation MRI data acquired in biomimetic microfiber phantoms that mimic hollow …

[HTML][HTML] Physical and digital phantoms for validating tractography and assessing artifacts

I Drobnjak, P Neher, C Poupon, T Sarwar - Neuroimage, 2021 - Elsevier
Fiber tractography is widely used to non-invasively map white-matter bundles in vivo using
diffusion-weighted magnetic resonance imaging (dMRI). As it is the case for all scientific …

[HTML][HTML] Production and cross-sectional characterization of aligned co-electrospun hollow microfibrous bulk assemblies

FL Zhou, GJM Parker, SJ Eichhorn… - Materials …, 2015 - Elsevier
The development of co-electrospun (co-ES) hollow microfibrous assemblies of an
appreciable thickness is critical for many practical applications, including filtration …

[HTML][HTML] Axon mimicking hydrophilic hollow polycaprolactone microfibres for diffusion magnetic resonance imaging

FL Zhou, Z Li, JE Gough, PLH Cristinacce, GJM Parker - Materials & design, 2018 - Elsevier
Highly hydrophilic hollow polycaprolactone (PCL) microfibres were developed as building
elements to create tissue-mimicking test objects (phantoms) for validation of diffusion …

Direct jet coaxial electrospinning of axon‐mimicking fibers for diffusion tensor imaging

C Hu, M Grech‐Sollars, B Statton, Z Li… - Polymers for …, 2023 - Wiley Online Library
Hollow polymer microfibers with variable microstructural and hydrophilic properties were
proposed as building elements to create axon‐mimicking phantoms for validation of …

Co-electrospraying of tumour cell mimicking hollow polymeric microspheres for diffusion magnetic resonance imaging

FL Zhou, HH Wu, DJ McHugh, I Wimpenny… - Materials Science and …, 2019 - Elsevier
Diffusion magnetic resonance imaging (dMRI) is considered as a useful tool to study solid
tumours. However, the interpretation of dMRI signal and validation of quantitative …

[HTML][HTML] Stability and reproducibility of co-electrospun brain-mimicking phantoms for quality assurance of diffusion MRI sequences

M Grech-Sollars, FL Zhou, AD Waldman, GJM Parker… - Neuroimage, 2018 - Elsevier
Grey and white matter mimicking phantoms are important for assessing variations in
diffusion MR measures at a single time point and over an extended period of time. This work …

Coaxial electrospun biomimetic copolymer fibres for application in diffusion magnetic resonance imaging

FL Zhou, DJ McHugh, Z Li, JE Gough… - Bioinspiration & …, 2021 - iopscience.iop.org
Objective. The use of diffusion magnetic resonance imaging (dMRI) opens the door to
characterizing brain microstructure because water diffusion is anisotropic in axonal fibres in …

Design and evaluation of a diffusion MRI fibre phantom using 3D printing

SO Abu-Sardanah, U Hussain, J Moore… - … 2018: Physics of …, 2018 - spiedigitallibrary.org
Diffusion weighted magnetic resonance imaging (dMRI) has enabled the in vivo imaging of
structures with a highly fibrous composition, such as brain white matter due to the ability to …