Aggregation‐enhanced theranostics: AIE sparkles in biomedical field

M Kang, Z Zhang, N Song, M Li, P Sun, X Chen… - …, 2020 - Wiley Online Library
Theranostics referring to the ingenious integration of diagnostics and therapeutics has
garnered tremendous attention in these years as it provides a promising opportunity for …

Aggregation-induced emission-active nanostructures: beyond biomedical applications

MH Chua, KLO Chin, XJ Loh, Q Zhu, J Xu - ACS nano, 2023 - ACS Publications
The discovery of aggregation-induced emission (AIE) phenomenon in 2001 has had a
significant impact on materials development across different research disciplines. AIE-active …

Performance enhancement of the lateral flow immunoassay by use of composite nanoparticles as signal labels

X Yin, S Liu, D Kukkar, J Wang, D Zhang… - TrAC Trends in Analytical …, 2024 - Elsevier
The lateral flow immunoassay (LFIA) strip has been one of the classic but dominant tools in
the point of care (POC) detection with multiple advantages (eg, portability and simplicity). As …

AIE luminogens as fluorescent bioprobes

G Niu, R Zhang, X Shi, H Park, S Xie, RTK Kwok… - TrAC Trends in …, 2020 - Elsevier
Organic fluorescent bioprobes provide robust and powerful analytical techniques for direct
detection and monitoring of important biological species and their related biological …

Killing G (+) or G (−) bacteria? The important role of molecular charge in AIE‐active photosensitizers

X Shi, SHP Sung, JHC Chau, Y Li, Z Liu… - Small …, 2020 - Wiley Online Library
Bacterial infections pose a serious threat to human health. Photodynamic therapy is an
effective medical treatment to solve the problems raised by antibiotic resistant bacteria. But it …

Versatile peptide-based nanosystems for photodynamic therapy

Q Li, R Ming, L Huang, R Zhang - Pharmaceutics, 2024 - mdpi.com
Photodynamic therapy (PDT) has become an important therapeutic strategy because it is
highly controllable, effective, and does not cause drug resistance. Moreover, precise …

An easily available ratiometric reaction-based AIE probe for carbon monoxide light-up imaging

J Wang, C Li, Q Chen, H Li, L Zhou, X Jiang… - Analytical …, 2019 - ACS Publications
Carbon monoxide (CO) is a significant gasotransmitter that naturally modulates inflammatory
responses. Visualization of CO in situ would help to reveal its physiological/pathological …

A molecular chameleon for mapping subcellular polarity in an unfolded proteome environment

TC Owyong, P Subedi, J Deng, E Hinde… - Angewandte …, 2020 - Wiley Online Library
Environmental polarity is an important factor that drives biomolecular interactions to regulate
cell function. Herein, a general method of using the fluorogenic probe NTPAN‐MI is reported …

Innovative synthetic procedures for luminogens showing aggregation‐induced emission

D Yan, Q Wu, D Wang, BZ Tang - … Chemie International Edition, 2021 - Wiley Online Library
As a consequence of their intrinsic advantageous properties, luminogens that show
aggregation‐induced emission (AIEgens) have received increasing global interest for a …

Tuning push–pull electronic effects of AIEgens to boost the theranostic efficacy for colon cancer

HT Feng, S Zou, M Chen, F Xiong, MH Lee… - Journal of the …, 2020 - ACS Publications
Colon cancer is one of the most common cancers with high mortality in humans. Early
diagnosis and treatment of colon cancer is of great significance for cancer therapy …