The complexity and heterogeneity of schizophrenia symptoms challenge an objective
diagnosis, which is typically based on behavioral and clinical manifestations. Moreover, the …

Schizophrenia is a severe psychiatric disorder with a lifetime prevalence of about 1%.
People with schizophrenia have a 4-fold higher prevalence of metabolic syndrome than the …

Cognitive impairment is a well-recognized key feature of schizophrenia. Here we review the
evidence on (1) the onset and sensitive periods of change in cognitive impairment before …

Cognitive impairment is a core characteristic of schizophrenia, but its underlying neural
mechanisms remain poorly understood. Reduced brain-derived neurotrophic factor (BDNF) …

Background Prefrontal abnormalities in schizophrenia have consistently emerged from
resting state and cognitive neuroimaging studies. However, these correlative findings …

Transcranial direct current stimulation (TDCS) is a technique with which neuronal activity,
and therefore potentially behavior, is modulated by applying weak electrical currents to the …

We addressed the relationship between white matter architecture, represented by MRI
fractional anisotropy (FA), and cognition in individuals with first-episode psychosis (FEP) by …

Schizophrenia is a mental disorder characterized by episodes of psychosis; major symptoms
include hallucinations, delusions, and disorganized thinking. More recent theories focus on …

Abstract Background and Hypothesis Cognitive impairment is a hallmark of schizophrenia,
but no effective treatment is available to date. The underlying pathophysiology includes …

Objective Cognitive deficits are core symptoms of schizophrenia; however, their
pathophysiological mechanisms are still unclear. A sensory gating deficit, as reflected by …