Designer drugs: mechanism of action and adverse effects

D Luethi, ME Liechti - Archives of toxicology, 2020 - Springer
Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex

AO Ceceli, CW Bradberry, RZ Goldstein - Neuropsychopharmacology, 2022 - nature.com
A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

An updated review on synthetic cathinones

J Soares, VM Costa, ML Bastos, F Carvalho… - Archives of …, 2021 - Springer
Cathinone, the main psychoactive compound found in the plant Catha edulis Forsk.(khat), is
a β-keto analogue of amphetamine, sharing not only the phenethylamine structure, but also …

Khat and synthetic cathinones: a review

MJ Valente, P Guedes de Pinho… - Archives of …, 2014 - Springer
For centuries,'khat sessions' have played a key role in the social and cultural traditions
among several communities around Saudi Arabia and most East African countries. The …

Comprehensive review of cardiovascular toxicity of drugs and related agents

P Mladěnka, L Applová, J Patočka… - Medicinal research …, 2018 - Wiley Online Library
Cardiovascular diseases are a leading cause of morbidity and mortality in most developed
countries of the world. Pharmaceuticals, illicit drugs, and toxins can significantly contribute to …

Exploring the role of nanomedicines for the therapeutic approach of central nervous system dysfunction: at a glance

MM Rhaman, MR Islam, S Akash, M Mim… - Frontiers in Cell and …, 2022 - frontiersin.org
In recent decades, research scientists, molecular biologists, and pharmacologists have
placed a strong emphasis on cutting-edge nanostructured materials technologies to …

Mechanisms of action and persistent neuroplasticity by drugs of abuse

ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - Elsevier
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Abuse potential and toxicity of the synthetic cathinones (ie,“Bath salts”)

AL Riley, KH Nelson, P To, R López-Arnau, P Xu… - Neuroscience & …, 2020 - Elsevier
The synthetic cathinones are derived from the naturally occurring drug cathinone found in
the khat plant (Catha edulis) and have chemical structures and neurochemical …

Neuropathology of substance use disorders

JL Cadet, V Bisagno, CM Milroy - Acta neuropathologica, 2014 - Springer
Addictions to licit and illicit drugs are chronic relapsing brain disorders that affect circuits that
regulate reward, motivation, memory, and decision-making. Drug-induced pathological …

Recent progress in the development of advanced element-block materials

M Gon, K Tanaka, Y Chujo - Polymer Journal, 2018 - nature.com
An element-block is defined as a minimum functional unit composed of heteroatoms. The
concept of 'element-block material'for designing advanced materials was proposed in 2015 …