Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …

Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

The alkylation of amines with either alcohols or carboxylic acids represents a mild and safe
alternative to the use of genotoxic alkyl halides and sulfonate esters. Here we report two …

Amino acids are naturally occurring and structurally diverse metabolites in biological system,
whose potentials for chemical expansion, however, have not been fully explored. Here, we …

Propanediol is an important building block as a component used in the manufacture of
unsaturated polyester resin, antifreeze, biofuel, nonionic detergent, etc. Commercial …

Carboxylic acid reductases (CARs) are biocatalysts of industrial importance. Their
properties, especially their poor stability, render them sub-optimal for use in a bioindustrial …

Carboxylate reductases (CARs) are valuable catalysts for the selective one‐step reduction
of carboxylic acids to their corresponding aldehydes. In recent years, numerous new CARs …

Carboxylic acid reductases (CARs) catalyze the conversion of carboxylic acids to aldehydes,
which are a valuable class of chemicals for many consumer and industrial applications …

Rapid evolution of enzyme activities is often hindered by the lack of efficient and affordable
methods to identify beneficial mutants. We report the development of a new growth-coupled …

Background Cinnamyl alcohol is not only a kind of flavoring agent and fragrance, but also a
versatile chemical applied in the production of various compounds. At present, the …