In the context of precision medicine, disease treatment requires individualized strategies
based on the underlying molecular characteristics to overcome therapeutic challenges …

Cancer remains the second most common cause of death after cardiovascular diseases,
accounting for nearly 10 million deaths in 2020. Although the incidence of cancer increases …

Proteomics is the study which involves analyzing proteins from both a basic science and a
clinical perspective. Proteins can be assessed for abundance, diversity of proteoforms owing …

Urothelial bladder cancer (UBC) is a heterogeneous multifactorial malignancy with a high
recurrence rate. Current procedures for UBC diagnosis suffering from the lack of clinical …

The involvement of the actin-regulatory protein, gelsolin (GSN), in neoplastic transformation
has been reported in different cancers including bladder cancer. However, the exact …

High-throughput proteomics has become an exciting field and a potential frontier of modern
medicine since the early 2000s. While significant progress has been made in the technical …

This paper presents the construction and characterization of an amperometric
immunosensor based on the graphene/gold nanoparticles (AuNPs/GO) nanocomposite for …

Bladder cancer (BC) represents a significant global health challenge, contributing to high
mortality rates. The progression of non-muscle invasive bladder cancer to muscle-invasive …

Two-dimensional difference gel electrophoresis (2D-DIGE) is an elegant gel electrophoretic
analytical tool for comparative protein assessment. It is based on two-dimensional gel …

Ubiquitination is a post-translational modification, in which a small regulatory protein (~ 8.6
kDa) is tagged as a single moiety or as a chain to target proteins. Ubiquitination is the most …