Oxidative stress related diseases in newborns

Y Ozsurekci, K Aykac - Oxidative medicine and cellular …, 2016 - Wiley Online Library
We review oxidative stress‐related newborn disease and the mechanism of oxidative
damage. In addition, we outline diagnostic and therapeutic strategies and future directions …

Melatonin's role as a co-adjuvant treatment in colonic diseases: A review

E Esteban-Zubero, L López-Pingarrón… - Life sciences, 2017 - Elsevier
Melatonin is produced in the pineal gland as well as many other organs, including the
enterochromaffin cells of the digestive mucosa. Melatonin is a powerful antioxidant that …

Glutathione peroxidase in health and diseases

E Sarıkaya, S Doğan - Glutathione system and oxidative stress in …, 2020 - books.google.com
The aim of this study is to give information to readers about the importance of glutathione
peroxidase. The physiopathology of most diseases is not fully elucidated currently; however …

Models of necrotizing enterocolitis

CM Lopez, MES Sampah, JW Duess, A Ishiyama… - Seminars in …, 2023 - Elsevier
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. The mortality of patients with NEC is …

Oxidative stress and necrotizing enterocolitis: pathogenetic mechanisms, opportunities for intervention, and role of human milk

A Aceti, I Beghetti, S Martini, G Faldella… - … medicine and cellular …, 2018 - Wiley Online Library
This review will examine the role of oxidative stress (OS) in the pathogenesis of necrotizing
enterocolitis (NEC) and explore potential preventive and therapeutic antioxidant strategies …

Sepsis and oxidative stress in the newborn: from pathogenesis to novel therapeutic targets

C Poggi, C Dani - Oxidative medicine and cellular longevity, 2018 - Wiley Online Library
Sepsis is at present one of the leading causes of morbidity and mortality in the neonatal
population. Together with inflammation, oxidative stress is involved in detrimental pathways …

Innate immune signaling in the pathogenesis of necrotizing enterocolitis

DJ Hackam, A Afrazi, M Good… - Journal of Immunology …, 2013 - Wiley Online Library
Necrotizing enterocolitis (NEC) is a challenging disease to treat, and caring for patients
afflicted by it remains both frustrating and difficult. While NEC may develop quickly and …

Necrotizing enterocolitis: LPS/TLR4-induced crosstalk between canonical TGF-β/Wnt/β-catenin pathways and PPARγ

A Gomart, A Vallée, Y Lecarpentier - Frontiers in Pediatrics, 2021 - frontiersin.org
Necrotizing enterocolitis (NEC) represents one of the major causes of morbidity and
mortality in premature infants. Several recent studies, however, have contributed to a better …

Oxidative stress-mediated damage in newborns with necrotizing enterocolitis: a possible role of melatonin

L Marseglia, G D'Angelo, S Manti… - American Journal of …, 2015 - thieme-connect.com
Background Necrotizing enterocolitis is a gastrointestinal surgical emergency in premature
neonates. Free radicals have been linked to the development of the disease in infants …

Update in pathogenesis and prospective in treatment of necrotizing enterocolitis

G Terrin, A Scipione, M De Curtis - BioMed research …, 2014 - Wiley Online Library
Necrotizing enterocolitis (NEC) is among the most common and devastating diseases in
neonates and, despite the significant advances in neonatal clinical and basic science …