It is estimated that 20000 to 30000 new patients are diagnosed with osteonecrosis annually
accounting for approximately 10% of the 250000 total hip arthroplasties done annually in the …

Osteonecrosis of the femoral head (ONFH) is a devastating and complicated disease with an
unclear etiology. Femoral head‐preserving surgeries have been devoted to delaying and …

The physiopathology of the femoral head bone necrosis is similar for children and for adults.
The disease is characterized by apoptosis of bone cells–bone marrow and bone forming …

Osteonecrosis is a phenomenon involving disruption to the vascular supply to the femoral
head, resulting in articular surface collapse and eventual osteoarthritis. Although alcoholism …

Background and purpose—The value of core decrompression for treatment of osteonecrosis
of the femoral head (ONFH) is unclear. We investigated by a literature review whether …

The use of bisphosphonates in the treatment of avascular necrosis of the femoral head is an
encouraging but relatively new option with most published data being derived from small …

Background Cell-therapy has been promoted among the therapeutic arsenal that can aid in
bone formation and remodeling, in early stages of osteonecrosis of the femoral head …

Introduction: Osteonecrosis of femoral head (ONFH) leads to hip osteoarthritis (HOA);
among joint preserving treatments (JPT), the role of core decompression (CD) is still …

In search of the sequence of pathogenic events leading to glucocorticoid-induced
osteonecrosis, we determined the molecular, biomechanical, cellular, and vascular changes …

Aims Earlier studies dealing with trends in the management of osteonecrosis of the femoral
head (ONFH) identified an increasing rate of total hip arthroplasties (THAs) and a …