The incidence of melanoma, among the most lethal cancers, is widespread and increasing.
Metastatic melanoma has a poor prognosis, representing about 90% of skin cancer …

Diagnostic immunohistochemistry (dIHC) has been practiced for several decades, with an
ongoing expansion of applications for diagnostic use, and more recently for detection of …

Histiocytic neoplasms are rare hematologic disorders accounting for less than 1% of cancers
of the soft tissue and lymph nodes. Clinical presentation and prognosis of these disorders …

Strides in melanoma surveillance, detection, and treatment continue to be made. The
American Joint Committee on Cancer Eighth Edition Cancer Staging System has improved …

Immunohistochemistry (IHC) is an important adjunct in the diagnosis of neoplastic skin
diseases. In addition to the many established IHC markers currently in use, new markers …

Opinion statement In the era of molecular targeted therapy, the accurate detection of BRAF
mutation in melanoma has become increasingly important. With the advances of molecular …

Background Unicystic ameloblastoma, an odontogenic neoplasm, presents clinical and
radiographic similarities with dentigerous and radicular cysts, non‐neoplastic lesions. It is …

Image-based analysis as a rapid method for mutation detection can be advantageous in
research or clinical settings when tumor tissue is limited or unavailable for direct testing …

We tested and clinically validated a targeted next-generation sequencing (NGS) mutation
panel using 80 formalin-fixed, paraffin-embedded (FFPE) tumor samples. Forty non-small …

Abstract BRAF p. V600E mutations are detected in greater than 50% of pediatric
Langerhans cell histiocytosis (LCH) lesions. However, the use of mutation‐specific BRAF …